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Methylone d3

Manufactured by Cayman Chemical
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Sourced in United States

Methylone-d3 is a deuterated analog of the designer drug methylone. It is commonly used as an internal standard in analytical chemistry applications involving the detection and quantification of methylone and related compounds.

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Lab products found in correlation

Methylone, by Cerilliant (3 mentions) Methanol, by Carlo Erba (2 mentions) Acetonitrile, by Carlo Erba (2 mentions) 4 chloromethcathinone, by Cayman Chemical (1 mentions) Ethyl acetate, by Carlo Erba (1 mentions) Sodium hydroxide (naoh), by Carlo Erba (1 mentions) Formic acid, by Carlo Erba (1 mentions) Chloroform, by Carlo Erba (1 mentions)

Close spelling variants of this product

Methylone

4 protocols using methylone d3

1

Quantitative Analysis of Synthetic Drugs

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MDMA, MDA, HMMA, HMA, methylone and HMMC standards were purchased from Cerilliant (Round Rock, TX, USA). Deuterated internal standards (ISTD) MDMA-d5, MDA-d5 and methylone-d3 were acquired from Cayman Chemical (Ann Arbor, MI, USA). Standards were stored at −20 °C until analysis. LC-MS grade water, methanol, acetonitrile, formic acid, chloroform and ethyl acetate were obtained from Carlo Erba (Cornaredo, Italia). Ammonium hydroxide (25% purity) and hydrochloric acid (37% purity) were purchased from Honeywell Fluka™ (Morristown, NJ, USA).
Poyatos L., Lo Faro A.F., Berardinelli D., Sprega G., Malaca S., Pichini S., Huestis M.A., Papaseit E., Pérez-Mañá C., Busardò F.P, & Farré M. (2022). Methylone and MDMA Pharmacokinetics Following Controlled Administration in Humans. International Journal of Molecular Sciences, 23(23), 14636.
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2

Quantitative Analysis of Novel Stimulants

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Methylone, MDC and HMMC were supplied by Cerilliant (Round Rock, TX, USA). Internal standard (IS), Methylone-d3, was purchased from Cayman Chemical (Ann Arbor, MI, USA). Standards were stored at −20 °C until analysis. LC-MS-grade water, methanol, acetonitrile, formic acid and ethyl acetate were obtained from Carlo Erba (Cornaredo, Italy). Ammonium hydroxide (25% purity) and hydrochloric acid (37% purity) were supplied by Honeywell Fluka™ (Morristown, NJ, USA).
Di Giorgi A., Sprega G., Poyatos L., Papaseit E., Pérez-Mañá C., Di Trana A., Varì M.R., Busardò F.P., Pichini S., Zaami S., Lo Faro A.F, & Farré M. (2023). Sweat Testing for the Detection of Methylone after Controlled Administrations in Humans. International Journal of Molecular Sciences, 24(8), 7395.
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3

Quantification of Novel Psychoactive Substances

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4-chloromethcathinone (Clephedrone, 4-CMC), N-ethyl Pentedrone (α-Ethylaminopentiophenone, NEP), N-ethyl Hexedrone (α-Ethylaminohexanophenone, NEH), and Methylone-d3 (deuterated internal standard, IS) were purchased from Cayman (Ann Arbor, MI, USA). Pentafluoropropionic anhydride (PFPA) was supplied from Merk Life Science SRL (Milano, Italy).
LC-MS/MS grade water, methanol, acetonitrile, LC-MS grade formic acid and ethyl acetate, ammonium hydrogen carbonate and sodium hydroxide were purchased from Carlo Erba (Cornaredo, Italy).
Nuñez-Montero M., Lombroni C., Maida N.L., Rotolo M.C., Pichini S., Papaseit E., Hladun O., Ventura M., Poyatos L., Pérez-Mañá C., Farré M, & Marchei E. (2023). GC–MS/MS Determination of Synthetic Cathinones: 4-chloromethcathinone, N-ethyl Pentedrone, and N-ethyl Hexedrone in Oral Fluid and Sweat of Consumers under Controlled Administration: Pilot Study. International Journal of Molecular Sciences, 24(11), 9387.
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4

Quantitative Analysis of Novel Psychoactive Substances

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Methylone, MDC and HMMC were supplied from Cerilliant (Round Rock, TX, USA). The internal standard (IS), Methylone-d3, was purchased from Cayman Chemical (Ann Arbor, MI, USA). Standards were stored at −20 °C until analysis. LC-MS grade water, acetonitrile, methanol, formic acid, ethyl acetate and chloroform were purchased from Carlo Erba (Cornaredo, Italy). In total, 25% purity ammonium hydroxide and 37% purity hydrochloric acid were obtained from Honeywell Fluka™ (Morristown, NJ, USA). SalivetteR tubes with cotton swab were purchased from Sarstedt (Nümbrecht, Germany).
Sprega G., Di Giorgi A., Poyatos L., Papaseit E., Pérez-Mañá C., Tini A., Pichini S., Busardò F.P., Lo Faro A.F, & Farré M. (2023). Usefulness of Oral Fluid for Measurement of Methylone and Its Metabolites: Correlation with Plasma Drug Concentrations and the Effect of Oral Fluid pH. Metabolites, 13(4), 468.
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