Achieva 3 t mri unit

All patients scanned suffered no migraine attacks in the previous 24 h. MRI acquisition was performed with a Philips Achieva 3 T MRI unit (Philips Healthcare, Best, The Netherlands), using a 32-channel head coil in the MRI facility at the University of Valladolid (Valladolid, Spain).
First, high-resolution 3D anatomical T1-weighted images were acquired using the following parameters: Turbo field echo (TFE) sequence, repetition time (TR) = 8.1 ms, echo time (TE) = 3.7 ms, flip angle = 8°, 256 × 256 matrix size, spatial resolution of 1 × 1 × 1 mm³ and 160 slices that cover the whole brain.
Then, diffusion-weighted data were obtained. The parameters employed in the acquisition were TR = 9000 ms, TE = 86 ms, flip angle = 90°, single-shell acquisition with 61 gradient directions and b-value = 1000 s/mm², one baseline volume, 128 × 128 matrix size, spatial resolution of 2 × 2 × 2 mm³ and 66 slices that cover the whole brain.
Both T1 and diffusion-weighted data were collected between May 2014 and July 2018 in a unique MRI session, starting with the T1 scan. For a single subject, the time for both scans was approximately 18 minutes.

In the same session, high‐resolution 3D T1‐ and diffusion‐weighted images (DWI) were acquired using a Philips Achieva 3 T MRI unit (Philips Healthcare, Best, The Netherlands) with a 32‐channel head coil.
For the anatomical T1‐weighted images, the following acquisition parameters were used: Turbo Field Echo sequence, repetition time (TR) = 8.1 ms, echo time (TE) = 3.7 ms, flip angle = 8°, 256 × 256 matrix size, 1 × 1 × 1 mm³ of spatial resolution and 160 slices covering the whole brain.
DWI were acquired using the next parameters: TR = 9,000 ms, TE = 86 ms, flip angle = 90°, 61 gradient directions, one baseline volume, b‐value = 1,000 s/mm², 128 × 128 matrix size, 2 × 2 × 2 mm³ of spatial resolution and 66 axial slices covering the whole brain.
The acquisition protocol was the same that was used in Planchuelo‐Gómez, et al. (2020a, 2020b). Further details can be found in Supplementary File 1.

Images were acquired for migraine patients after at least 24 h from the last migraine attack. High-resolution 3D T1-weighted and diffusion-weighted MRI data were acquired using a Philips Achieva 3 T MRI unit (Philips Healthcare, Best, The Netherlands) with a 32-channel head coil in the MRI facility at the Universidad de Valladolid (Valladolid, Spain).
For the anatomical T1-weighted images, the following acquisition parameters were used: Turbo Field Echo (TFE) sequence, repetition time (TR) = 8.1 ms, echo time (TE) = 3.7 ms, flip angle = 8°, 256 × 256 matrix size, 1 × 1 × 1 mm³ of spatial resolution and 160 slices covering the whole brain.
Diffusion-weighted images (DWI) were acquired using the next parameters: TR = 9000 ms, TE = 86 ms, flip angle = 90°, 61 gradient directions, one baseline volume, b-value = 1000 s/mm², 128 × 128 matrix size, 2 × 2 × 2 mm³ of spatial resolution and 66 axial slices covering the whole brain.
T1 and diffusion-weighted scans were acquired during the same session, starting with the T1 scan followed by the diffusion-weighted scan, between May 2014 and July 2018. Total acquisition time for each subject was around 18 min.