Syringetin

Mobile phases of acetonitrile and methanol for HPLC (high-performance liquid chromatography) and phenolic acids, including caffeic acid, ferulic acid, naringenin, neoeriocitrin, and hesperetin were purchased from Sigma-Aldrich (St. Louis, MO, USA). Dihydroflavonols (dihydroquercetin dihydromyricetin and dihydrokaempferol), eriodictyol, homoeriodictyol, quercetin 3,3’-dimethyl ether, quercetin 3-methyl ether, chrysoeriol, and isokaempferide were obtained from BioBioPha Co., Ltd. (Kunming, China). Eriocitrin, baicalein, luteolin, quercetin, kaempferol, isorhamnetin, and SAM were from Aladdin (Shanghai, China). Apigenin, myricetin, and 7,8-dihydroxyflavone hydrate were from TCI (Shanghai, China) and tricin was purchased from ChromaDex (Irvine, CA, USA). Tricetin and syringetin were purchased from Extrasynthese (Lyon, France) and baicalein 7-methyl ether was purchased from Shanghai yuanye Bio-Technology Co., Ltd. (Shanghai, China). RPMI-1640 medium, fetal bovine serum (FBS), HEPES, and trypsin-EDTA were purchased from Gibco (Waltham, MA, USA). Cell Counting Kit-8 was purchased from Dojindo Technology (Shanghai, China).

Acetonitrile and methanol of HPLC grade were purchased from Sigma-Aldrich (St. Louis, MO, USA). Quercetin 3-methyl ether, eriodictyol, ampelopsin (dihydromyricetin), taxifolin (dihydroquercetin), aromadendrin (dihydrokaempferol), tamarixetin, quercetin 3,3'-dimethyl ether, isokaempferide, chrysoeriol, homoeriodictyol, and isoferulic acid were purchased from BioBioPha Co., Ltd (Kunming, China), and oroxylin A was purchased from Shanghai Yuanye Bio-Technology Co., Ltd (Shanghai, China). Laricitrin, syringetin, and tricetin were from Extrasynthese (Lyon, France), and tricin was from ChromaDex (Irvine, CA, USA). Quercetin, isorhamnetin, kaempferol, luteolin, baicalein, eriocitrin, SAM, and formic acid for HPLC were obtained from Aladdin (Shanghai, China). Myricetin, apigenin, and 7,8-dihydroxyflavone hydrate were purchased from TCI (Shanghai, China). Caffeic acid, naringenin, hesperetin, neoeriocitrin, and ferulic acid were also purchased from Sigma-Aldrich.

Laricitrin and syringetin were purchased from Extrasynthese (Genay, France) (Purity >99.3% by HPLC analysis); Piceatannol, resveratrol, lipopolisaccharide (LPS) and cisplatin were obtained from Sigma Chemical (St. Louis, MO). Recombinant Human (rh) IL-10 protein was obtained from R&D Systems (Minneapolis, MN).