Gnawing blocks

Manufactured by Bio-Serv

Sourced in United States

Gnawing blocks are made of wood or other suitable materials and are designed to provide a chewing surface for rodents. These blocks serve as enrichment items to support natural behaviors and dental health.

Automatically generated - may contain errors

Lab products found in correlation

Sasco sprague dawley rats, by Charles River Laboratories (1 mentions)

2 protocols using gnawing blocks

Sprague Dawley Rat Model for Research

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For these studies, 7‐week‐old and 8‐month‐old (retired breeders) male Sprague Dawley rats (Harlan Laboratories/Envigo, Indianapolis, IN, USA) were used. Herein age refers to age at the time of surgery. Rats were pair housed in individually ventilated caging (Tecniplast, West Chester, PA, USA) with a tunnel and gnawing blocks (Bio‐Serv, Prospect, CT, USA) for enrichment. Bedding was a mixture of corn cob and processed paper. Purina Mills International #5001 was fed ad libitum. Filtered tap water treated with ultraviolet light was provided ad libitum in bottles. Sentinel results from Charles River Laboratories (Wilmington, MA, USA) International Rat Prevalent PRIA testing were negative for all pathogens in the housing room. All animals were allowed to acclimate for at least 2 weeks before any procedures were performed. After each procedure, a divider was temporarily placed in the cage for better monitoring of postoperative recovery. Animals were randomly allocated to treatment groups.

Cheng A., Krishnan L., Tran L., Stevens H.Y., Xia B., Lee N., Williams J.K., Gibson G, & Guldberg R.E. (2018). The Effects of Age and Dose on Gene Expression and Segmental Bone Defect Repair After BMP‐2 Delivery. JBMR Plus, 3(2), e10068.

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Female Sprague Dawley Rat Study

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For these studies, 13-week-old female SASCO Sprague Dawley rats (Charles River Laboratories, Inc.) were used. Rats were pair housed in individually ventilated caging (Tecniplast) with a tunnel and gnawing blocks (Bio-Serv) for enrichment. Bedding was a mixture of corn cob and processed paper. Purina Mills International #5001 was fed ad libitum. Filtered tap water treated with ultraviolet light was provided ad libitum in bottles. Sentinel results from Charles River Laboratories International Rat Prevalent PRIA testing were negative for all pathogens in the housing room. All animals were allowed to acclimate for at least 2 weeks before any procedures were performed. Following each procedure, a divider was temporarily placed in the cage for better monitoring of post-operative recovery. Animals were randomly allocated to treatment groups. All procedures in this study were approved by the Georgia Institute of Technology Institutional Animal Care and Use Committee in compliance with Federal regulations governing the protection of animals in research.

Cheng A., Krishnan L., Pradhan P., Weinstock L.D., Wood L.B., Roy K, & Guldberg R.E. (2019). Impaired Bone Healing Following Treatment of Established Nonunion Correlates With Serum Cytokine Expression. Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 37(2), 299-307.

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