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P38 inhibitor sb 203580

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The P38 inhibitor (SB-203580) is a small molecule that inhibits the p38 mitogen-activated protein kinase (MAPK) pathway. It functions by binding to and inhibiting the activity of the p38 MAPK enzyme, which is involved in various cellular processes, including inflammation, cell growth, and differentiation.

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Lab products found in correlation

Ar n 20 antibodies, by Santa Cruz Biotechnology (2 mentions) Phospho p38 thr180 tyr182 antibody, by Cell Signaling Technology (2 mentions) Ar antibody for ip, by Merck Group (2 mentions) Gapdh 6c5, by Santa Cruz Biotechnology (2 mentions) Anti mouse rabbit second antibody for western blot, by Thermo Fisher Scientific (2 mentions)

2 protocols using p38 inhibitor sb 203580

1

Western Blot Antibody Validation

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GAPDH (6c5) and AR (N-20) antibodies were purchased from Santa Cruz Biotechnology. Phospho-p38 (Thr180/Tyr182) antibody was from Cell Signaling Technology. AR antibody for IP was from Millipore. The p38 and Phospho-Hsp27 (ser78) antibody were purchased from One World Lab. Anti-mouse/rabbit second antibody for Western Blot was from Invitrogen. The p38 inhibitor (SB-203580) was from Apexbio. Doc was from Fisher Scientific.
Cui Y., Sun Y., Hu S., Luo J., Li L., Li X., Yeh S., Jin J, & Chang C. (2016). Neuroendocrine prostate cancer (NEPCa) increased the neighboring PCa chemo-resistance via altering the PTHrP/p38/Hsp27/androgen receptor (AR)/p21 signals. Oncogene, 35(47), 6065-6076.
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2

Western Blot Antibody Validation

Check if the same lab product or an alternative is used in the 5 most similar protocols
GAPDH (6c5) and AR (N-20) antibodies were purchased from Santa Cruz Biotechnology. Phospho-p38 (Thr180/Tyr182) antibody was from Cell Signaling Technology. AR antibody for IP was from Millipore. The p38 and Phospho-Hsp27 (ser78) antibody were purchased from One World Lab. Anti-mouse/rabbit second antibody for Western Blot was from Invitrogen. The p38 inhibitor (SB-203580) was from Apexbio. Doc was from Fisher Scientific.
Cui Y., Sun Y., Hu S., Luo J., Li L., Li X., Yeh S., Jin J, & Chang C. (2016). Neuroendocrine prostate cancer (NEPCa) increased the neighboring PCa chemo-resistance via altering the PTHrP/p38/Hsp27/androgen receptor (AR)/p21 signals. Oncogene, 35(47), 6065-6076.
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