Mass hunter workstation software for icp ms

To evaluate the release kinetics of Sr²⁺ from the hydrogels during the neutralization process (samples were collected when saline was changed after 30 min, 1, 2, 3, 24, and 48 h), inductively coupled plasma mass spectrometry (ICP-MS) was used. Lyophilized hydrogel samples were dissolved in deionized water and high-purity nitric acid solution. To complete the reaction, samples were kept for 20 min at room temperature. Then, samples were transferred to a Mars 6 microwave oven (CEM Corporation, Matthews, NC, United States) where the temperature was increased up to 150°C, within 30 min and held for 30 min at 150°C. The solution, cooled to room temperature, was filtered through a filter with a pore size of 12–15 μm (Filtres Fioroni, Ingré, France), quantitatively transferred to volumetric flasks, and diluted to 50 ml with deionized water. An Agilent 7700x ICP-MS instrument with Mass Hunter Workstation software for ICP-MS (version B.01.03, Tokyo, Japan) was used for the analysis of elements.
Strontium content in the hydrogel sample was calculated using the following equation: ${\mathrm{m}}_{S{r}^{2+}}\left(\mathrm{g}\right)=\frac{2\times M_{S{r}^{2+}}}{M_{SrRan}}\times {\mathrm{m}}_{SrRan},$ where $m_{S{r}^{2+}}$ is the weight of Sr²⁺ in the hydrogel sample, g; $M_{S{r}^{2+}}$ is molecular weight of Sr²⁺, g/mol; M_SrRan is molecular weight of SrRan, g/mol; m_SrRan is the weight of the SrRan in the hydrogel sample.