Advantage workstation aw

PET scans were acquired using either Signa PET/MRI 3 Tesla system, GE Healthcare, Waukesha, WI, USA (N = 46) or PET/CT, Discovery-690, GE Healthcare (N = 39).
Fasting condition was requested on the day of ⁶⁸Ga-PSMA PET/MRI and PET/CT scan.
PET scans were acquired from the skull base to mid-thigh (5–6 FOVs, 4 min/FOV), and started approximately 60 min (mean ± SD, 63 ± 6 min) after injection of 111–273 MBq (Mean ± SD, 168 ± 33 MBq) of ⁶⁸Ga-PSMA. PET images, acquired with either PET/MRI or PET/CT scanner, were reconstructed using fully 3D ordered subset expectation-maximization (OSEM) algorithm, time-of-flight (TOF) and point-spread-function (PSF).
⁶⁸Ga PSMA PET image read-out was performed by two Nuclear Medicine physicians on an Advantage Workstation (AW, General Electric Healthcare, Waukesha, WI, USA) and the presence of ⁶⁸GA-PSMA intraprostatic increased uptake was considered positive for malignancy.

PET scans were acquired using either Signa PET/MRI 3 Tesla system (GE Healthcare, Waukesha, WI, USA; N = 39) or PET/CT systems (Discovery-STE or Discovery-690, GE Healthcare, Waukesha, WI, USA; N = 41). [⁶⁸Ga]Ga-PSMA-11 PET/MRI scans were acquired according to a previously published protocol [16 (link)]. PET/CT scans were acquired according to the joint EANM and SNMMI procedure guidelines for PCa imaging [17 (link)]. [⁶⁸Ga]Ga-PSMA-11 PET image read-out was performed by two Nuclear Medicine Physicians with knowledge of all the available patients’ clinical and imaging information on the Advantage Workstation (AW, General Electric Healthcare, Waukesha, WI, USA), on which PET, MRI, CT, and fused images could be visualized in axial, coronal, and sagittal planes. In the event of disagreement or uncertain findings, the images were re-examined, and a consensus was reached. The whole-body distribution pattern of [⁶⁸Ga]Ga-PSMA-11 was qualitatively assessed, and the presence of increased uptake deviating from the physiological distribution of the tracer was considered positive for malignancy [18 (link)]. The anatomical sites were defined based on MR or CT images co-registered with PET examinations.