Prism 7.0 for mac

Clinical and laboratory data were analyzed with respect to the detection of TLR4-SI on day 1 post-CPB. t-test was used to analyze continuous variables and Mann-Whitney test for comparison of non-parametric data. Categorical variables were compared using Fisher exact test. Normality was determined using D’Agostino and Pearson test. Demographic and clinical variables recognized in unadjusted comparisons as statistically significant at p-value of less than 0.1 were selected for inclusion in a logistic regression model. Data are presented as mean and 95% confidence interval (95%CI) of mean if data were normally distributed, or median and interquartile (Q25, Q75%) range if data were not normally distributed. Within group values were compared using ANOVA with repeated measure and Tukey’s multiple comparisons test, or Friedman test and Dunn’s multiple comparisons test if data were not normally distribution. Data and statistical analyses were performed using Prism 7.0 for Mac OSX (Graph Pad software, Inc) and STATISTICA 12.0 for Windows (StatSoft Inc. Oklahoma, USA). p-values less than 0.05 were considered statistically significant.

All statistical analyses were performed using GraphPad Prism 7.0 for Mac (San Diego, CA, USA). Histological and functional data were analyzed using 2-way analysis of variance (ANOVA) with Tukey’s test to determine significance of BoNT-A use. Bladder weight data were analyzed using one-way ANOVA with post hoc Bonferroni.

Paired 1-tailed Student’s t-tests were performed (Figures 2E–G only) using Microsoft Excel version 15.3 (Microsoft, Redmond, WA, USA). ANOVA analysis followed by Bonferroni’s pairwise multiple comparison post hoc tests were performed using Prism 7.0 for Mac OSX (GraphPad Software, San Diego, CA, USA). Differences were considered significant when P < 0.05; degrees of significance are indicated by letters or asterisks as defined in the figure legends.