Anti α4β7

Manufactured by Thermo Fisher Scientific

Sourced in United States

Anti-α4β7 is a laboratory product used for the detection and quantification of the α4β7 integrin, a cell surface protein involved in cell adhesion and trafficking. It is commonly used in research applications to study immune cell function and inflammatory processes.

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Lab products found in correlation

2 protocols using anti α4β7

Comprehensive Immunostaining Panel for Immune Cell Analysis

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Anti-Nono (Cat# 11058-1-AP and 66361-1-Ig) was from Proteintech. Anti-Elk3 (Cat# NBP1-83960) was from Novus Biologicals. Anti-Tmem241 (Cat# 203644-T32) was from Sinobiological. Anti-Lineage cocktail (Cat# 88-7772-72), Anti-CD127 (A7R34), anti-Sca-1 (D7), anti-Flt3 (A2F10), anti-α₄β₇ (DATK32), anti-Id2 (ILCID2), anti-PLZF (Mags.21F7), anti-Eomes (Dan11mag), anti-NKp46 (29A1.4), anti-NK1.1 (PK136), anti-CD45 (30-F11), anti-CD25 (PC61.5), anti-Gata3 (TWAJ), anti-RORγt (AFKJS-9), anti-Bcl11b (1F8H9), anti-CD3 (17A2), anti-CD19 (1D3), anti-KLRG1 (2F1), anti-CD90 (HIS51), anti-IL-22 (IL22JOP), anti-Ki67 (SolA15), anti-CD45.2 (104), anti-BrdU (BU20A), anti-PD-1 (J43) and anti-CD45.1 (A20) were purchased from eBiosciences (San Diego, USA). Anti-c-Kit (2B8), anti-CD150 (TC15-12F12.2), anti-CD48 (HM48-1), and anti-CD49a (HMα1) were purchased from Biolegend (California, USA). Anti-β-actin (Cat# RM2001) was purchased from Beijing Ray Antibody Biotech. Paraformaldehyde (PFA) and 4’,6-diamidino-2-phenylindole (DAPI) were from Sigma. IL-22 ELISA kit was purchased from Neobioscience.

Liu N., He J., Fan D., Gu Y., Wang J., Li H., Zhu X., Du Y., Tian Y., Liu B, & Fan Z. (2022). Circular RNA circTmem241 drives group III innate lymphoid cell differentiation via initiation of Elk3 transcription. Nature Communications, 13, 4711.

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Immunophenotyping of T-cells from Murine MLN

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The MLN was homogenized, and single cell suspensions were incubated with anti-CD3, anti-CD4, anti-IL-17A and anti-α4β7 antibodies following the manufacturer’s intracellular staining protocol (eBiosciences).

Meng J., Banerjee S., Li D., Sindberg G.M., Wang F., Ma J, & Roy S. (2015). Opioid Exacerbation of Gram-positive sepsis, induced by Gut Microbial Modulation, is Rescued by IL-17A Neutralization. Scientific Reports, 5, 10918.

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