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Circle CVI is a comprehensive cardiac imaging software suite designed to assist healthcare professionals in the analysis and visualization of cardiovascular data. The core function of Circle CVI is to provide advanced tools for the assessment of cardiac structure, function, and perfusion from various imaging modalities, including magnetic resonance imaging (MRI), computed tomography (CT), and echocardiography.

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2 protocols using circle cvi

1

Cardiovascular MRI Imaging Analysis

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Cardiovascular magnetic resonance studies were analysed offline using Circle CVI (Circle Cardiovascular Imaging, CVI42 V.5.3.6, Calgary Canada). T1, T2 maps, late gadolinium enhancement and cine-derived volumetric and functional sequences were analysed by experienced observers (MD, TS and TAK). Native T1and T2 measurements were taken from septal segments, although we also report results for global T1. T1 mapping acquired using shortened modified Look-Locker inversion recovery was excluded from native T1 analysis but not from extracellular volume analysis. Areas of late gadolinium enhancement were included for calculating global extra cellular volume. Late gadolinium enhancement was adjudicated by consensus of expert observers (GPM and JRA) who were blinded to all participant details (including whether scans were from patients or volunteers) and classified as ischaemic or non-ischaemic (midwall or epicardial) pattern. Right ventricular insertion point enhancement in isolation was not considered pathological.
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2

Pancreatic Manganese Quantification

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Magnetic resonance images were analysed offline using Circle CVI (Circle Cardiovascular Imaging, CVI42 v5.13.5). Quantitative analysis of manganese accumulation was performed by measuring T1 relaxation time in the region of interest drawn within the head, body and tail of the pancreas and compared with the left ventricular blood pool. T1 maps were generated using commercially available software (CVI42, Circle cardiovascular imaging) and applying a three‐parameter non‐linear curve fitting as described previously.
18 (link) Analysis was performed by experienced observers (SJ, TS).
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