E cadherin 610182

Antibodies against Slug (SC‐10436), Twist (SC‐15393) and β‐actin (sc‐47778) were purchased from Santa Cruz (CA, USA); those against cleaved caspase‐3 (9661), cleaved PARP (9541), TGF‐β (3711), Smad2 (5339), p‐Smad2 (3108), Smad3 (9523) and p‐Smad3 (9520) were from Cell Signaling Technology (MA, USA); and those against N‐cadherin (610921) and E‐cadherin (610182) were from BD, NJ, USA. Anti–HAS2 (ab140671), anti–Vimentin (3634‐100) and anti–zeb1 (HPA027524) were from Abcam (MA, USA), Biovision (CA, USA) and Sigma (MO, USA), respectively. Hyaluronan (GLR001, low molecular weight; GLR004, middle molecular weight; GLR002, high molecular weight) was purchased from R&D Systems (MN, USA). 4‐Methylumbelliferone (M1381) and SB431542 (S4317) was purchased from Sigma (MO, USA).

Antibodies against human CD147 was produced by our lab; Par3 (07‐330) and integrin α5 (MAB1956Z) were obtained from Merck Millipore (Darmstadt, Germany); β‐catenin (51067‐2‐AP), occludin (13409‐1‐AP), lamin B (66045‐1‐AP), α‐tubulin (11224‐1‐AP), and Src (60315‐1‐AP) were purchased from Proteintech (Wuhan, China); phosphotyrosine (ARR8004) was obtained from Antibody Revolution (South San Francisco, CA); E‐cadherin (ET1607‐75) and β‐actin (M1210‐2) were purchased from Huabio (Hangzhou, China); multidrug resistance–associated protein 2 (MRP2, ab3373) and mouse CD147 (ab34016) were obtained from Abcam (Cambridge, UK); ZO‐1 (sc‐10804), integrin β1 (sc‐13590), phosphorylated Src (Tyr416, sc‐101802), and ubiquitin (sc‐271289) were purchased from Santa Cruz Biotechnology (Dallas, TX); Na⁺/taurocholate cotransporting polypeptide (orb13624), mouse MRP2 (orb11075), and CBLL1/Hakai (orb2538) were obtained from Biorbyt (Cambridge, UK); E‐cadherin (610182) was from BD Biosciences (Franklin Lakes, NJ); Alexa Fluor 555 phalloidin (A34055) was from Invitrogen (Carlsbad, CA); CellLight Lysosomes‐RFP (C10597) was purchased from Cell Signaling Technology; Src family activator (sc‐3052) was purchased from Santa Cruz Biotechnology; Src kinase inhibitor Src I‐1, MG132, and chloroquine were from Sigma (St. Louis, MO); TGF‐β1 (100‐21‐10VG) was obtained from Peprotech (Rocky Hill, NJ).