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Pyrazole

Manufactured by Tokyo Chemical Industry

Pyrazole is a heterocyclic organic compound consisting of a five-membered ring with two adjacent nitrogen atoms. It is a colorless, crystalline solid that is soluble in organic solvents. Pyrazole serves as a core functional group in various chemical compounds and is widely used in the synthesis of various pharmaceuticals and agrochemicals.

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2 protocols using pyrazole

1

Characterization of Lignocellulosic Biomass

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Hard red winter wheat straw was collected from south-eastern Washington. The wheat straw sample was air-dried and milled to a specific size (mesh −40/+60), which was composed of 22.4 ± 0.1% lignin, 40.8 ± 0.6% cellulose, 29.2 ± 0.2% hemicellulose, and 3.4 ± 0.3% ash, and 3.2 ± 0.1% extractives. L(+)-Lactic acid (90% solution in water), ethanol (95%), choline chloride (99%), pyridine (99+%), and aniline (99+%) were purchased from Fisher Scientific. Pyrazole (>98%) was purchased from TCI America. Alkali Lignin (AL, CAS: 8068-05-1) and Technical Sodium Lignosulfonate (LS, CAS: 8061-51-6) samples were, respectively, purchased from Sigma-Aldrich and Spectrum Chemical. All chemicals were used as received.
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2

Synthesis of Pyrazole Derivatives

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EXAMPLE 1

This Example illustrates a method of synthesizing compounds of formulae (I) and (II) in accordance with an embodiment of the present invention.

General Chemistry Methods. The reactions were performed under positive pressure of nitrogen with oven-dried glassware. Pyrazole and 3,5-dimethylPyrazole were purchased from TCI America. Formaldehyde, acetaldehyde, styrene oxide, N-succinimide, THF, and methanol were purchased from Sigma-Aldrich (St. Louis, Mo.).

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