Ge discovery ls

Manufactured by GE Healthcare

Sourced in United States

The GE Discovery LS is a computed tomography (CT) imaging system designed for general radiological examinations. It provides high-quality diagnostic images to support medical professionals in their clinical decision-making process.

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Lab products found in correlation

Ge discovery st, by GE Healthcare (2 mentions) Ge discovery ste pet ct scanner, by GE Healthcare (1 mentions) Ge discovery ste, by GE Healthcare (1 mentions) Ge discovery st, by Siemens (1 mentions) Somatom definition as, by Siemens (1 mentions)

5 protocols using ge discovery ls

Multimodal Imaging in Epilepsy Assessment

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All images were acquired at 3.0T field strength using dedicated MRI epilepsy protocols. 3D T1-weighted IR prepped gradient echo scan sequences were used for quantitative image analysis, and their parameters are described (Table S1). In addition, fluid-attenuated inversion recovery (FLAIR) images (slice thickness 1–4mm), and T2-weighted images (thickness 1–3mm) were included as part of the clinical protocol, complementing qualitative image interpretation. Acknowledging the importance of thin FLAIR slices in the clinical identification of small lesions, both institutions (UCSF and UAB) routinely used 1mm volumetric coronal acquisitions after 2011. Prior to this, FLAIR sequences were 3mm thick, and anything above this was an exception.
FDG-PET scans were acquired in the interictal state under standard resting conditions (eyes closed, dimmed ambient light) using CTI ECAT HR+, GE-Discovery LS, and GE-Discovery STE PET/CT scanners. Approximately 45 minutes following the intravenous administration of 2.6–13.2 mCi 18F-labeled FDG, 3D PET images of the brain were obtained from the vertex to skull base (slice thickness 3.0–4.25mm). Images were attenuation-corrected using noncontrast CT transmission information.

Tan Y.L., Kim H., Lee S., Tihan T., Ver Hoef L., Mueller S.G., Barkovich A.J., Xu D, & Knowlton R. (2017). Quantitative surface analysis of combined MRI and PET enhances detection of focal cortical dysplasias. NeuroImage, 166, 10-18.

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PET/CT Imaging Protocol for 18F-FDG

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The PET/CT equipment was a hybrid system (GE Discovery LS). The imaging agent was ¹⁸F-FDG (Nanjing Jiangyuan Andy Electronics Research and Development Co. Ltd. Fuzhou Branch). All patients fasted for 6–8 h before the examination, ensuring that their fasting blood glucose values were within the acceptable range. Each patient received an intravenous injection of 4.44–5.55 MBq/kg ¹⁸F-FDG, before resting quietly supine for 45–60 min in a darkened room. Image acquisition ranged from the cranial crest to the middle femur. The CT scanning parameters were 120 KV, 150 mA, and a scanning layer thickness of 4.25 mm. PET scan parameters were 2.5 min/bed for a total of 6–8 beds, three-dimensional acquisition, and an acquisition time of approximately 18–20 min. After imaging was completed, the CT data were used for attenuation correction, and the data were reconstructed by the iterative method for image fusion to obtain PET, CT, and PET/CT fusion images in cross-section, the sagittal plane, and the coronal plane, respectively.

Liao S., Wei W., Zhang S., Zeng T., Chen H., Zheng W., Chen C., Ji Z, & Zheng B. (2021). Modified method to improve the diagnostic efficiency of 18F-FDG PET/CT in regional lymph node metastasis of esophageal squamous cell carcinoma. Annals of Translational Medicine, 9(20), 1549.

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Phantom and Patient Studies on GE PET/CT Scanners

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Phantom studies were acquired on a GE Discovery LS (General Electric Medical Systems, Milwaukee, WI), comprised of a full 4.0×8.1×30 mm bismuth germanate (BGO) block detector ring of 150 mm field‐of‐view operating in the 2D mode.⁽¹¹⁾ Patient studies were acquired on a GE Discovery ST, which is constructed with a full 6.0×6.0×30 mm BGO block detector ring of 157 mm FOV also operating in the 2D mode.⁽¹²⁾ The CT employed on these scanners is a GE LightSpeed 16‐slice detector array with a tube current range of 10–140 mA, peak kilovoltage range of 80–140 kVp, and maximum gantry rotation frequency of 3 Hz.

Nye J.A., Tudorascu D., Esteves F, & Votaw J.R. (2016). Quantitative outcome of registration methods for correcting cardiac drift in cardiac PET/CT imaging. Journal of Applied Clinical Medical Physics, 17(2), 542-549.

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PET/CT Imaging Protocol for Cancer Staging

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PET/CT imaging was performed at diagnosis or staging and at treatment simulation. No restrictions were placed on the PET/CT system used. Staging imaging was performed on GE Discovery LS, GE Discovery ST, GE Discovery STE (GE Medical Systems, Milwaukee, WI), Philips Gemini TrueFlight (Philips Healthcare, Andover, MA), Siemens BioGraph HiRes Model 1080, and Siemens Biograph TruePoint Model 1093 (Siemens, Erlangen, Germany) scanners. Before 2012, simulation scans were performed on a GE Discovery ST platform, and after 2012 a Siemens Somatom Definition AS platform was used. The PET/CT protocol has been previously described¹¹ (link) and consists of 8-hour fasting with blood glucose less than 160 mg/dL before injection of 10 to 18 mCi FDG, 45 to 60 minutes of tracer uptake time, and PET/CT acquisition with helical CT for attenuation correction.

Prionas N.D., von Eyben R., Yi E., Aggarwal S., Shaffer J., Bazan J., Eastham D., Maxim P.G., Graves E.E., Diehn M., Gensheimer M.F, & Loo BW J.r. (2018). Increases in Serial Pretreatment 18F-FDG PET-CT Metrics Predict Survival in Early Stage Non-Small Cell Lung Cancer Treated With Stereotactic Ablative Radiation Therapy. Advances in Radiation Oncology, 4(2), 429-437.

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Cerebral Glucose Metabolism Imaging Protocol

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All patients underwent interictal ¹⁸F-FDG-PET for cerebral metabolic rate for glucose utilization measurement using a GE Discovery LS PET/CT scanner (GE Medical Systems, USA) and (Nihon-Kohden Corporation, Japan). Axial raw data were obtained on a PET scanner 60 minutes after the intravenous injection of 18F-fluorodeoxyglucose (FDG; 370 MBq). The acquisition time was approximately 20 minutes. The axial images were reconstructed using a Shepp–Logan filter (cutoff frequency, 5 cycles per pixel) and realigned in the coronal and sagittal planes. Spatial resolution was 6.1 mm × 6.1 mm × 4.3 mm. Visual PET analysis was performed by a trained examiner during the presurgical phase and before 3D-iEEG procedure, using a colored scale allowing detection of metabolic changes, each color corresponding to a 15% variation of FDG uptake. Extent of hypometabolic areas was classified as focal (≤3 cm) or regional (>3 cm). PET and CT were routinely coregistered using ANATOMIST software (SHFJ, CEA, Orsay, France). In addition, individual statistical analysis using SPM5 software (Welcome Department of Cognitive Neurology, London, UK) was secondarily performed.

Yang P.F., Shang M.C., Lin Q., Xiao H., Mei Z., Jia Y.Z., Liu W, & Zhong Z.H. (2016). Three-dimensional intracranial EEG monitoring in presurgical assessment of MRI-negative frontal lobe epilepsy. Medicine, 95(50), e5192.

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