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Fvbn202 mice

Manufactured by Charles River Laboratories

FVBN202 mice are a specific inbred strain of laboratory mice developed and maintained by Charles River Laboratories. These mice are characterized by their genetic homogeneity and are commonly used in various research applications.

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2 protocols using fvbn202 mice

1

Cytotoxic CD8 T Cell Proliferation

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C57BL/6, T bet knock-out B6.129S6-Tbx21tm1Glm (T-bet-), female Balb/c and parental FVB mice were purchased from Jackson Laboratories ((Bar Harbor, ME)). Female Her2/neu transgenic FVBN202 mice were obtained from Charles River Laboratories (Wilmington, MA). FVBN202 mice over-express a non-activated rat neu transgene under the regulation of the mouse mammary tumor virus promoter (28 (link)). T-bet- mice are lack of T-box transcription factor, TBX21 (29 (link)). C57BL/6 and T-bet- mice were used to study ex vivo and in vivo proliferation of cytotoxic CD8 T cells. Female FVB and FVB202 mice were used to establish MMC tumor model whereas female Balb/c mice were utilized to establish 4T1-luc orthotopic breast tumor model.
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2

Murine Models for Tumor Immunology

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C57BL/6, T bet knock-out B6.129S6-Tbx21 tm1Glm (T-bet -), female Balb/c and parental FVB mice were purchased from Jackson Laboratories ((Bar Harbor, ME)). Female Her2/neu transgenic FVBN202 mice were obtained from Charles River Laboratories (Wilmington, MA). FVBN202 mice over-express a non-activated rat neu transgene under the regulation of the mouse mammary tumor virus promoter (28) (link). T-bet -mice are lack of T-box transcription factor, TBX21 (29) (link). C57BL/6 and T-bet -mice were used to study ex vivo and in vivo proliferation of cytotoxic CD8 T cells. Female FVB and FVB202 mice were used to establish MMC tumor model whereas female Balb/c mice were utilized to establish 4T1-luc orthotopic breast tumor model.
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