Achieva 3 tesla mri scanner

Imaging was performed on a Philips Achieva 3 Tesla MRI scanner (Philips, Erlangen, The Netherlands).
The structural MRI protocol consisted of a localizer scan, a high resolution three-dimensional T1-weighted volume (sequence parameters: TR 20 ms; TE 4.6 ms; flip angle 10°; inversion time 800 ms; turbo field echo factor 65; sense factor 2; field of view 256 × 256×180 mm³; 1 × 1 x 1 mm³ isotropic voxel size) and a T2*-weighted multi-slice acquisition (T2*-weighted fast field echo (T2*-FFE), sequence parameters:TR = 3,500 ms; TE = 35 ms; flip angle = 90 deg; sense factor = 2; 70 axial slices; 2 x 2 x 2 mm³ isotropic voxel size).
Language task-related functional volumes were acquired using a T2*-weighted echo-planar imaging (EPI) sequence (TR = 2 s; TE = 35 ms; flip angle = 80°; 31 axial slices with a 240 × 240 mm² field of view and 3.75 × 3.75 × 3.75 mm³ isotropic voxel size). In the three runs, 192, 194, and 194 T2*-weighted volumes were acquired for the production, listening, and reading sentence tasks, respectively.
Resting-state functional volumes (N = 240) were acquired as a single 8 min long run using the same T2*-weighted EPI sequence. Immediately prior to scanning, the participants were instructed to ‘keep their eyes closed, to relax, to refrain from moving, to stay awake and to let their thoughts come and go’.

A Philips Achieva 3 Tesla MRI scanner with a 32-channel head coil was used to collect the imaging data for all participants. This involved a 5-min T1-weighted scan to create a standard high-resolution anatomical image of the brain (1 mm isotropic voxels) before a 15-min eyes-open resting-state scan was obtained. The scans captured the entire brain using gradient echo echo-planer imaging oriented parallel to the AC-PC line with the following parameters: 450 volumes, TR = 2,000 ms, TE = 35 ms, flip angle = 80°, 3 × 3 × 4 mm³ voxels. Respiratory and cardiac fluctuations were monitored using equipment also provided by Philips.

T1W three-dimensional (3D) turbo field echo (TFE) images of all fifteen Beagles were performed with a Phillips Achieva 3 Tesla MRI Scanner (Phillips Medical Systems, Eindhoven, The Netherlands) with a circular surface coil with a diameter of 11 cm. Examinations were performed under general anesthesia and artificial ventilation. For premedication either acepromazine (0.05 mg/10 kg BW IM) or diazepam (0.5 mg/kg BW IV) together with levomethadone (0.2–0.6 mg/kg BW IV) were used. Anesthesia was induced with propofol (2 mg/kg BW IV) and maintained with isoflurane in air and oxygen. For image acquisition, dogs were placed in dorsal recumbency and the following protocol parameters were used: a repetition time of 11.2 ms to 11.5 ms with an echo time of 5.2 ms to 5.3 ms, a slice thickness of 0.7 mm and a slice interval of 0.0 mm. The flip angle was 8° and the field of view (FOV) varied from 210 mm to 220 mm.

Diffusion-weighted images were previously acquired for 60 healthy right-handed (30 female, mean age = 30.1, age range = 20–53) belonging to the BIL&GIN database (Brain Imaging of Lateralization by the Groupe d’Imagerie Fonctionnelle; Mazoyer et al., 2016 (link)). All the subjects gave written informed consent to participate in the study, which was approved by the local ethics committee (CCPRB Basse-Normandie). Imaging was performed on a Philips Achieva 3 Tesla MRI scanner using a single-shot spin-echo echo-planar sequence with 21 non-collinear diffusion gradient directions (b = 1000 s/mm²). Seventy axial slices parallel to the AC-PC plane were acquired from the bottom of the cerebellum to the vertex. Imaging parameters were as follows: TR = 8500 ms, TE = 81 ms, angle = 90°, SENSE reduction factor = 2.5, FOV 224 mm, acquisition matrix 112 × 112, 2 mm × 2 mm × 2 mm isotropic voxel. The series of 21 directions was acquired twice by reversing the gradients’ polarity, for a total of 42 diffusion-weighted volumes. To improve the signal-to-noise ratio, a second series of 42 volumes was acquired leading to a total acquisition time of 15 min 30 s.

The experimental MEG and fMRI data from sixteen participants with average age 15.8 years were described in our previous study and a detailed description of the data and paradigms can be found in (Wang et al., 2012 (link)). MEG data were acquired using a 275-channel whole head MEG system (VSM Med-Tech Ltd., Port Coquitlam, BC, Canada) sampled at 6 kHz and fMRI data were acquired on a Philips Achieva 3-Tesla MRI scanner with Dual Quasar gradients (Philips Medical Systems, Best, The Netherlands). During the scan, the participants performed a narrative comprehension task including three conditions (story listening, question answering, and pure tone listening). In the current study, we only focused on the contrast of story listening versus tone listening. The group fMRI results were used as spatial priors for MEG source reconstructions (see Fig. 2). Three clusters that survived the thresholding (height threshold T = 5.78 and extent threshold k = 50 voxels, p < 0.005 Family-Wise Error rate corrected) were projected onto the template cortical mesh in Fig. 2-1 and correspond approximately to left inferior gyrus (IFG) and bilateral superior temporal gyrus (STG).

Imaging was performed on a Philips Achieva 3Tesla MRI scanner. The structural MRI protocol consisted of a localizer scan, a high resolution 3D T₁-weighted volume acquisition (TR = 20 ms; TE = 4.6 ms; flip angle = 10°; inversion time = 800 ms; turbo field echo factor = 65; sense factor = 2; matrix size = 256×256×180; 1 mm³ isotropic voxel size) and a T₂^*-weighted multi-slice acquisition (T₂*-FFE sequence, TR = 3,500 ms; TE = 35 ms; flip angle = 90°; sense factor = 2; 70 axial slices; 2 mm³ isotropic voxel size). Functional volumes were acquired with a T₂^*-weighted echo planar imaging acquisition (192 volumes; TR = 2 s; TE = 35 ms; flip angle = 80°; 31 axial slices; 3.75 mm³ isotropic voxel size) covering the same field of view than the T₂*-FFE acquisition.