Symbia t2 system

For gamma-camera acquisitions, 200 images of 1 second were acquired in planar mode on a 128 × 128 matrix using a Symbia T2 system (Siemens Medical Solutions, USA). For PET acquisitions, a 200 second volume was acquired in list-mode on a Discovery 710 system (General Electrics, Milwaukee, WI) and reconstructed to obtain 200 frames of 1 second (OSEM: 24 subsets and 2 iterations, no attenuation correction, reconstructed slice thickness of 3.27 mm, Butterworth post-filter with 6.4 mm cut-off).
Random blurred images were obtained by summing 40 randomly selected frames in the 200 frames available in each acquisition. Thirty datasets of 4 random blurred images were reconstructed for gamma-camera acquisition and another 30 datasets for PET acquisition.

The static part of the phantom derived from the segmentation of a late phase bone SPECT acquired for clinical purpose. This SPECT was acquired 3 hours after the administration of 10 MBq/kg of 99mTc-HDP on a dual head Symbia T2 system (Siemens Medical Solutions, Forcheim, Germany) using the following parameters: step and shoot mode (32 projections of 10 seconds, 128 × 128 matrix). The acquisition was reconstructed using an OSEM 2D algorithm (2 iterations, 10 subsets) with a reconstructed voxel size of 4.8 × 4.8 × 4.8 mm³.
Three tissues were segmented: soft tissues, kidneys and bones using thresholding and manual corrections. InVesalius software^{[2 ,3 ]} was used to perform thresholding.