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3 methoxy 4 hydroxycinnamic acid

Manufactured by Merck Group
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Sourced in Germany

3-methoxy-4-hydroxycinnamic acid is a chemical compound that is commonly used in laboratory settings. It is a white crystalline solid that is soluble in organic solvents. The compound has a molecular formula of C10H10O3 and a molecular weight of 178.18 g/mol. 3-methoxy-4-hydroxycinnamic acid is often used as a standard or reference material in various analytical techniques, such as high-performance liquid chromatography (HPLC) and mass spectrometry. Its specific function and intended use may vary depending on the research or analytical application.

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Lab products found in correlation

Fetal bovine serum (fbs), by Thermo Fisher Scientific (3 mentions) Dulbecco s modified eagle medium, by Thermo Fisher Scientific (2 mentions) Dulbecco s phosphate buffered saline, by Thermo Fisher Scientific (2 mentions) Gelatin, by Merck Group (2 mentions) Collagenase type 4, by Merck Group (2 mentions) Hydroxycinnamic acid, by Merck Group (1 mentions) 3 4 dihydroxyhydrocinnamic acid, by Merck Group (1 mentions) 3 5 dimethoxy 4 hydroxycinnamic acid, by Merck Group (1 mentions) 3 4 dihydroxycinnamic acid, by Merck Group (1 mentions) Trypsin, by Thermo Fisher Scientific (1 mentions) 4 dimethylaminopyridine, by Merck Group (1 mentions) 2 bromoethylamine hydrobromide, by Merck Group (1 mentions) P nitrophenyl chloroformate, by Merck Group (1 mentions) Dimethyl sulfoxide (dmso), by Merck Group (1 mentions) Deuterium oxide d2o, by Merck Group (1 mentions) N hydroxysuccinimide, by Merck Group (1 mentions) N 3 dimethylaminopropyl n ethylcarbodiimide hydrochloride, by Merck Group (1 mentions) Polyethylene glycol peg, by Merck Group (1 mentions) Endothelial growth media 2, by Lonza (1 mentions)

4 protocols using 3 methoxy 4 hydroxycinnamic acid

1

Biofunctionalized Hydrogel Characterization

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Gelatin (Gtn, type A from porcine skin, less than 300 bloom), laccase (lyophilized powder from mushroom, ≥4.0 units/mg), 3-methoxy-4-hydroxycinnamic acid (ferulic acid, FA), N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride (EDC), N-hydroxysuccinimide (NHS), dimethyl sulfoxide (DMSO), deuterium oxide (D2O), and collagenase type IV were purchased from Sigma-Aldrich (Saint Louis, MO) and used as obtained without purification. Dulbecco’s Phosphate-Buffered Saline (DPBS), Dulbecco’s Modified Eagle Medium (DMEM), and fetal bovine serum (FBS) were all purchased from Gibco, Invitrogen (Life Technologies, CA). Dialysis membrane (molecular cutoff = 3,500 Da) was purchased from Spectrum Laboratories (Rancho Dominguez, CA).
Park K.M, & Gerecht S. (2014). Hypoxia-Inducible Hydrogels. Nature communications, 5, 4075.
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2

Biofunctionalized Hydrogel Characterization

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Gelatin (Gtn, type A from porcine skin, less than 300 bloom), laccase (lyophilized powder from mushroom, ≥4.0 units/mg), 3-methoxy-4-hydroxycinnamic acid (ferulic acid, FA), N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride (EDC), N-hydroxysuccinimide (NHS), dimethyl sulfoxide (DMSO), deuterium oxide (D2O), and collagenase type IV were purchased from Sigma-Aldrich (Saint Louis, MO) and used as obtained without purification. Dulbecco’s Phosphate-Buffered Saline (DPBS), Dulbecco’s Modified Eagle Medium (DMEM), and fetal bovine serum (FBS) were all purchased from Gibco, Invitrogen (Life Technologies, CA). Dialysis membrane (molecular cutoff = 3,500 Da) was purchased from Spectrum Laboratories (Rancho Dominguez, CA).
Park K.M, & Gerecht S. (2014). Hypoxia-Inducible Hydrogels. Nature communications, 5, 4075.
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3

Hydroxycinnamic Acids Interactions with Cyclodextrins

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The following hydroxycinnamic acids and their derivatives were purchased from Sigma-Aldrich (Steinheim, Germany) and were used as received: 3,4-dihydroxycinnamic acid (caffeic acid, CAF), 3-methoxy-4-hydroxycinnamic acid (ferulic acid, FA), 4-hydroxycinnamic acid (p-coumaric acid, PCA), 3,5-dimethoxy-4-hydroxycinnamic acid (sinapic acid, SA), 3,4-dihydroxyhydrocinnamic acid (hydrocaffeic acid, HCA), and 3-methoxy-4-hydroxyhydrocinnamic acid (hydroferulic acid, HFA). Cyclodextrin (CD) hosts employed in the study included heptakis(2,6-di-O-methyl)-β-CD (DIMEB or DMB), heptakis(2,3,6-tri-O-methyl)-β-CD (TRIMEB or TMB), and hexakis(2,3,6-tri-O-methyl)-α-CD (TRIMEA or TMA).
Hunt L.E., Bourne S.A, & Caira M.R. (2020). Inclusion of Hydroxycinnamic Acids in Methylated Cyclodextrins: Host-Guest Interactions and Effects on Guest Thermal Stability. Biomolecules, 11(1), 45.
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4

Ferulic Acid-Crosslinked Gelatin Hydrogels

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Gelatin (Gtn, type A from porcine skin, <300 bloom), 3-methoxy-4-hydroxycinnamic acid (ferulic acid, FA), N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride (EDC), N-hydroxysuccinimide (NHS), dimethyl sulfoxide (DMSO), Dextran (Dex, MW 70,000), 2–bromoethylamine hydrobromide (BEAHB), triethylamine (TEA), 4–dimethylaminopyridine (DMAP), p–nitro–phenylchloroformate (PNC), poly(ethylene glycol) (PEG, MW 4000), tyramine (TA), laccase (lyophilized powder from mushroom, ≥4.0 units/mg), and deuterium oxide (D2O) were purchased from Sigma-Aldrich (Saint Louis, MO) and used as obtained without purification. Microbial transglutaminase (mTG) (Activa-TI) was purchased from Ajinomoto, Inc. Dulbecco’s Phosphate-Buffered Saline (DPBS), Dulbecco’s Modified Eagle Medium (DMEM), fetal bovine serum (FBS), and trypsin were all purchased from Gibco, Invitrogen (Life Technologies, CA). Dialysis membranes (molecular cutoff = 3500 Da; molecular cutoff = 6000–8000 Da) were purchased from Spectrum Laboratories (Rancho Dominguez, CA). Endothelial growth media-2 (EGM2) was purchased from Lonza (Walkersville, MD) and used to culture endothelial colony forming cells (ECFCs) (Lonza) on collagen I coated cell culture plates (BD Biosciences, Franklin Lakes, NJ).
Blatchley M., Park K.M, & Gerecht S. (2015). Designer Hydrogels for Precision Control of Oxygen Tension and Mechanical Properties. Journal of materials chemistry. B, Materials for biology and medicine, 3(40), 7939-7949.
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