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Copper 2 chloride dihydrate

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Copper(II) chloride dihydrate is a chemical compound with the formula CuCl2·2H2O. It is a crystalline solid that appears as blue-green crystals. The compound is commonly used as a precursor for other copper(II) compounds and in various industrial and laboratory applications.

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Lab products found in correlation

Hydrochloric acid (hcl), by Merck Group (12 mentions) Sodium hydroxide (naoh), by Merck Group (9 mentions) Nickel 2 chloride hexahydrate, by Merck Group (8 mentions) Ethanol, by Merck Group (7 mentions) Cobalt 2 chloride hexahydrate, by Merck Group (7 mentions) Polyvinylpyrrolidone, by Merck Group (6 mentions) Iron 3 chloride hexahydrate, by Merck Group (6 mentions) Silver nitrate, by Merck Group (5 mentions) Zinc chloride, by Merck Group (5 mentions) Potassium chloride (kcl), by Merck Group (5 mentions) Potassium hydroxide, by Merck Group (4 mentions) Oleylamine, by Merck Group (4 mentions) Toluene, by Merck Group (4 mentions) L ascorbic acid, by Merck Group (4 mentions) Chromium 3 chloride hexahydrate, by Merck Group (3 mentions) Manganese 2 chloride tetrahydrate, by Merck Group (3 mentions) Iron 3 chloride, by Merck Group (3 mentions) Ascorbic acid, by Merck Group (3 mentions) Hydrogen peroxide, by Merck Group (3 mentions) Cobalt 2 nitrate hexahydrate, by Merck Group (3 mentions)

Close spelling variants of this product

Copper(II) chloride (110 citations) Copper chloride (66 citations) Copper chloride dihydrate (16 citations) Copper (II) chloride dihydrate (CuCl2.2H2O, (10 citations)

76 protocols using copper 2 chloride dihydrate

1

Synthesis of Multimodal Nanoparticles

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Gold(III) chloride hydrate (HAuCl4), hydroquinone, cetyltrimethylammonium bromide (CTAB), sodium borohydride (NaBH4), silver nitrate (AgNO3), dopamine hydrochloride, bicine, N,N-dimethylformamide (DMF), copper(II) chloride dihydrate (CuCl2), and mouse serum were purchased from Sigma-Aldrich (Atlanta, GA, USA). Methoxyl poly(ethylene glycol) (PEG) thiol (HS-mPEG, Mw 5k Da) was purchased from Nanocs. Dulbecco’s modified Eagle’s medium (DMEM) was purchased from Thermo Fisher. All reagents were used without further purification. Distilled water was used to make aqueous solutions. Transmission electron microscopy (TEM) grids were purchased from Ted Pella, Inc.
Yim W., Zhou J., Mantri Y., Creyer M.N., Moore C.A, & Jokerst J.V. (2021). Gold Nanorod–Melanin Hybrids for Enhanced and Prolonged Photoacoustic Imaging in the Near-Infrared-II Window. ACS applied materials & interfaces, 13(13), 14974-14984.
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2

Screening of Inorganic Salts for Glycation Reactions

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Unless noted otherwise, all chemicals were obtained from Sigma-Aldrich. LCMS-grade methanol (Fisher Scientific, Schwerdte, Germany), formic acid (VWR, Darmstadt, Germany), ammonium formate and purified water from a Synergi-185 labwater system (Millipore, Schwalbach, Germany) were used for all experiments. d-Glucose monohydrate, sodium-l-lactate, sodium chloride, magnesium chloride hexahydrate, and calcium chloride dihydrate complied with the requirements of the European Pharmacopoeia and the ICH guideline Q3D (R1) on elemental impurities [25 , 26 ]. Glucosone [27 (link)], 3-DGal [28 (link)], and 3,4-DGE [17 (link)] were synthesized as reported previously. 3-DG was purchased from Chemos (Altdorf, Germany), 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid (HEPES) from Carl Roth (Karlsruhe, Germany), and hydrochloric acid (pro analysi) as well as sodium hydroxide (purity 99%) from Grüssing (Filsum, Germany). Eleven different inorganic salts were tested (all obtained from Sigma-Aldrich): lithium(I) chloride (purity ≥99.0%), aluminum(III) sulfate (99.99%), vanadium(III) chloride (97%), chromium(III) chloride hexahydrate (≥ 98%), manganese(II) chloride tetrahydrate (≥ 99.0%), iron(II) chloride (98%), iron(III) chloride (≥ 99.9%), nickel(II) chloride hexahydrate (99.99%), copper(II) chloride dihydrate (99.99%), zinc(II) chloride (99.99%), and molybdenum(IV) oxide (99%).
Gensberger-Reigl S., Auditore A., Huppert J, & Pischetsrieder M. (2020). Metal cations promote α-dicarbonyl formation in glucose-containing peritoneal dialysis fluids. Glycoconjugate Journal, 38(3), 319-329.
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3

Synthesis and Characterization of Zn-Doped CuO Nanostructures

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Zinc chloride (ZnCl2), Copper II chloride dihydrate (CuCl2∙2H2O), and Potassium hydroxide (KOH) were purchased from Sigma Aldrich, St. Louis, MI, USA. Structural analysis of Zn-doped CuO samples was carried out by using an X-ray diffractometer (Ultima IV Rigaku International Corp., Tokyo, Japan), scanned and recorded at 20–70° at CuK radiation (λ = 1.54056 Å). The surface morphology of pure and Zn-doped CuO-NSs was examined with a FE-SEM (QUANTA 250 FEI). X-ray photoelectron spectroscopy (XPS; Thermo specific model K-ALPHA) was used to investigate the surface elemental composition. To perform the antibacterial activity, four different bacterial strains were used, namely, Pseudomonas aeruginosa (ATCC® 10145), Klebsiella pneumonia (ATCC® BAA-1144), and Escherichia coli (ATCC® 33876) as gram-negative and while Staphylococcus aureus (ATCC® 11632) as gram-positive bacteria. Nutrient agar (Oxoid® CM0003) was purchased from Sigma-Aldrich.
Khalid A., Ahmad P., Alharthi A.I., Muhammad S., Khandaker M.U., Rehman M., Faruque M.R., Din I.U., Alotaibi M.A., Alzimami K, & Bradley D.A. (2021). Structural, Optical, and Antibacterial Efficacy of Pure and Zinc-Doped Copper Oxide Against Pathogenic Bacteria. Nanomaterials, 11(2), 451.
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4

Colloidal Nanoparticle Synthesis

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Copper (II) chloride dihydrate (CuCl2·2H2O, >99.0%), zinc chloride (ZnCl2, >98.0%), and tin (II) chloride (SnCl2, 98%) were purchased by Sigma-Aldrich Inc. and dehydrated in vacuum at 200 °C. Sulfur (S), oleylamine (OLA, 70%), toluene (99.9%), and ethanol (>99%) were also provided by Sigma-Aldrich Inc. and used without further purification.
Syafiq U., Ataollahi N., Maggio R.D, & Scardi P. (2019). Solution-Based Synthesis and Characterization of Cu2ZnSnS4 (CZTS) Thin Films. Molecules, 24(19), 3454.
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5

Synthesis of Biocompatible Nanoparticles

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Copper (II) chloride dihydrate (CuCl2·2H2O, ≥99%), Manganese (II) chloride tetrahydrate (MnCl2·4H2O, ≥98%), anhydrous sodium sulfide (Na2S, ≥98%) and monomethoxycarboxyl polyethylene glycol (mPEG-COOH, MW=2000, AR) were purchased from Sigma-Aldrich. Cell Counting Kit-8 (CCK-8) was purchased from Dojindo (Japan). All other reagents with analytical reagent grade were purchased from Sinopharm Chemical Reagent Co., Ltd. (China), and were used without further purification. The ultrapure water used in all experiments was obtained from a Millipore water purification system (resistivity 18.2 MΩ·cm).
Ke K., Yang W., Xie X., Liu R., Wang L.L., Lin W.W., Huang G., Lu C.H, & Yang H.H. (2017). Copper Manganese Sulfide Nanoplates: A New Two-Dimensional Theranostic Nanoplatform for MRI/MSOT Dual-Modal Imaging-Guided Photothermal Therapy in the Second Near-Infrared Window. Theranostics, 7(19), 4763-4776.
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6

Synthesis of Chalcogenide Nanostructures

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All chemicals used in the experiment were used as received, without further purification. Vanadium (IV) oxide acetylacetonate (VO(acac)2, ≥ 98%) was ordered from Merck KGaA. Selenium powder (Se, 99.99%), oleylamine (OLA, 70%), 1-dodecanethiol (1-DDT, ≥ 98%), Copper(II) chloride dihydrate (CuCl2·2H2O, 99.999%), and formamide were bought from Sigma-Aldrich. Sodium sulfide (Na2S, anhydrous) was purchased from Alfa Aesar. ACS grade chloroform (CHCl3, ≥ 99.8%), toluene (C7H8, ≥ 99.5%), and methanol (CH3OH, 99.8%) were bought from Fisher Scientific. Ethanol (C2H5OH, 100%) was ordered from Decon laboratories. FTO Soda Lime glass substrates were purchased from MSE Supplies.
Liu M., Lai C.Y., Zhang M, & Radu D.R. (2020). Cascade synthesis and optoelectronic applications of intermediate bandgap Cu3VSe4 nanosheets. Scientific Reports, 10, 21679.
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7

Synthesis of Luminescent Coordination Polymers

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Silver
nitrate (AgNO3), calcium chloride dihydrate (CaCl2·2H2O), sodium nitrate (NaNO3), potassium
chloride
(KCl), manganese chloride (MnCl2), copper II chloride dihydrate
(CuCl2·2H2O), magnesium chloride anhydrous
(MgCl2), aluminum chloride (AlCl3), iron III
chloride (FeCl3), dysprosium III chloride hexahydrate (DyCl3·6H2O), sodium citrate tribasic tetrahydrate
(HOC(COONa) (CH2COONa)2·4H2O),
hydrogen peroxide (H2O2), terbium III chloride
hexahydrate (TbCl3·6H2O), ytterbium III
chloride hexahydrate (YbCl3·6H2O), holmium
III chloride hexahydrate (HoCl3 ·6H2O),
lead chloride (PbCl2), sodium carbonate anhydrous (Na2CO3), sodium phosphate (Na3PO4), sodium sulfate (Na2SO4), sodium fluoride
(NaF), sodium acetate (CH3COONa), disodium tartrate, disodium
succinate, disodium malate, CTAB, polyethylene glycol 1500, and dodecanoic
acid were purchased from Sigma-Aldrich Company (South Korea). Fumaric
acid, p-toluene sulfonic acid (PTSA), and 3-(4-hydroxyphenyl)propanoic
acid were purchased from Merck (Germany). All solvents and chemicals
were used as received without purification. DI water filtered to 18
MΩ·cm was used in all experiments.
Shaban S.M., Lee J.Y, & Kim D.H. (2020). Dual-Surfactant-Capped Ag Nanoparticles as a Highly Selective and Sensitive Colorimetric Sensor for Citrate Detection. ACS Omega, 5(19), 10696-10703.
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8

Synthesis of Metal Xanthogenate Complexes

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Potassium ethyl xanthogenate (96%), antimony(III) chloride (SbCl3, ≥ 99.95%), copper(II) chloride dihydrate (CuCl2 2H2O, 99.99%), bismuth(III) chloride (BiCl3, ≥ 98%), Zinc(II) nitrate hexahydrate (Zn(NO3)2 6 H2O, ≥ 98%), methanol (99.8%), ethanol (95.0%), chloroform (CHCl3, ≥ 99%), Hexane (C6H14, ≥ 99%) were purchased from Sigma-Aldrich.
Alqahtani T., Khan M.D., Lewis D.J., Zhong X.L, & O’Brien P. (2021). Scalable synthesis of Cu–Sb–S phases from reactive melts of metal xanthates and effect of cationic manipulation on structural and optical properties. Scientific Reports, 11, 1887.
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9

Copper(II) Complex Characterization

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Copper(II) chloride dihydrate; 3,4-difluorophenylacetic acid; 2-methylpyridine; 3-methylpyridine; 2,2-diphenyl-1-picrylhydrazyl radical (DPPH); ascorbic acid; iron(II) sulfate; hydrogen peroxide; nitric acid; sodium salt of the salmon sperm DNA (SS-DNA); methanol; and DMSO were purchased from Sigma-Aldrich, St. Louis, MO, USA. These chemicals were used without any further treatment. Distilled water was used for the experimental work. The melting points of the synthesized complexes were recorded in a capillary tube using a digital electro-thermal melting point apparatus. Elemental analysis was performed on a Leco CHNS 932. A Perkin Elmer atomic absorption spectrometer A analyst 700 was used to determine the percentage of copper. The electronic absorption spectra (200–800 nm) of the complexes were recorded using a Perkin Elmer UV/Vis spectrometer Lambda 25 in DMSO solvent. A nicolet-6700 FT-IR spectrophotometer (Thermo Scientific, Waltham, MA, USA) was used to record FT-IR spectra in the range of 4000–400 cm−1, adopting the attenuated total reflectance (ATR) technique.
V.i.o.l.a., Muhammad N., Noor A., Sirajuddin M., Kubicki M., Rahim S., Samad A., Shujah S., Wadood A, & Ali S. (2023). Designing and Exploration of the Biological Potentials of Novel Centrosymmetric Heteroleptic Copper(II) Carboxylates. Pharmaceuticals, 16(10), 1462.
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10

Synthesis of Metal-Organic Complexes

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Oleic acid (technical grade, 90%), oleylamine (OLA) (technical grade, 70%), and toluene (HPLC grade, 99.9%) were purchased from Sigma-Aldrich. Reagent alcohol (histological grade, 90% ethyl alcohol, 5% methyl alcohol, and 5% butyl alcohol) was purchased from Fisher Scientific. Copper(II), zinc(II), and tin(IV)-diethyldithiocarbamate complexes were synthesized from sodium diethyldithiocarbamate trihydrate (ACS reagent, Sigma-Aldrich) and copper(II) chloride dihydrate (ACS grade, 99+%), zinc chloride (reagent grade, 98%), and tin(IV) chloride pentahydrate (98%), respectively. Sulfur was purchased from Cerac, Inc. (99.999%), and soda-lime glass (SLG) substrates were purchased from Valley Design Corp.
Pramanik S., Trejo N., Mclntire E., Hudson-Smith N.V., Tuga B., He J., Aydil E, & Haynes C.L. (2023). Transformations and Environmental Impacts of Copper Zinc Tin Sulfide Nanoparticles and Thin Films. ACS applied materials & interfaces, 15(20), 24978-24988.
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