Acute inflammation was induced by subcutaneous injection of 50 μL of λ-carrageenan (1% w/v in saline) into one of the hind paws of male nude mice (6 weeks, 20 g, Jackson Laboratory, Strain JAZ 007850 J:NU). An apparent edema response was observed 5 h after the λ-carrageenan injection. 150 μCi of radiotracer ([18F]compound 5 ) in 150 μL PBS was injected to mice through the tail vein (i.v.). Then, mice were anaesthetized with isoflurane (1.0 ~ 2.0%) and 90 min after injection of radiotracer, PET images were acquired for 20 min using an Inveon micro PET/CT Preclinical Scanner (Siemens). Subsequent CT images were acquired for 10 min.
Inveon micro pet ct preclinical scanner
Manufactured by Siemens
Sourced in United States
The Inveon micro PET/CT Preclinical Scanner is a small-animal imaging system designed for preclinical research. It combines Positron Emission Tomography (PET) and Computed Tomography (CT) technologies to enable high-resolution, non-invasive imaging of small laboratory animals. The system is capable of acquiring functional, anatomical, and molecular data in a single imaging session.
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Lab products found in correlation
2 protocols using inveon micro pet ct preclinical scanner
1
PET Imaging of Acute Inflammation
2
Imaging of Cochlear Implant Arrays
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Two cTFAs were independently imaged in a microcomputed tomography (CT) system, and one cTFA was imaged in a harvested feline cochlea after the electrical testing was completed. Imaging studies were conducted at the Emory School of Medicine's Center for Systems Imaging, Atlanta, GA, using a Siemens Inveon MicroPET:CT Preclinical Scanner (Siemens Medical Solutions USA, Inc.; Hoffman Estates, IL). The MicroCT images were made with a pixel size of 20 × 20 μm, slice thickness 21.5 μm, and resolution of 46.499 pixels per mm. Total slice size was 1152 × 1152 pixels (24.77 × 24.77 mm). The volume data was reoriented so that the distal end of the array was in the image plane. Measurements were made using OsiriX MD (Pixmeo SARL; Geneva, Switzerland) digital imaging software by a board-certified radiologist.
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