9-Fluorenylmethoxycarbonyl (Fmoc) protected L-α-amino acids and 1-[bis(dimethylamino)methylene]-1H-benzotriazolium hexafluorophosphate 3-oxide (HBTU) were purchased from GL Biochem (Shanghai, China). Piperidine (PPD) and trifluoroacetic acid (TFA) were purchased from Auspep (Melbourne, Australia). Fmoc-PAL-PEG-PS resins with substitution of 0.18 mmol/g were purchased from Applied Biosystems Inc. (Melbourne, Australia). Dimethylformamide (DMF), methanol, diethyl ether, and dichloromethane (DCM) were purchased from Merck (Melbourne, Australia). 3,6-Dioxa-1,8-octanedithiol (DODT), triisopropylsilane (TIPS), diisopropylethylamine (DIPEA) and trifluoromethanesulfonic acid (TFMSA) were purchased from Sigma-Aldrich (Sydney, Australia). 2,2-Dipyridyl disulfide (DPDS) was purchased from Fluka (Switzerland). Acetonitrile was purchased from BDH Laboratory Supplies, (Poole, UK). All other reagents were from Sigma-Aldrich (Sydney, Australia).
1 bis dimethylamino methylene 1h benzotriazolium hexafluorophosphate 3 oxide hbtu
Manufactured by GL Biochem
Sourced in China
1-[bis(dimethylamino)methylene]-1H-benzotriazolium hexafluorophosphate 3-oxide (HBTU) is a coupling agent used in organic synthesis, particularly in the field of peptide synthesis. It facilitates the formation of amide bonds between amino acids.
Automatically generated - may contain errors
Lab products found in correlation
Acetonitrile, by Avantor (2 mentions)
Trifluoromethanesulfonic acid tfmsa, by Merck Group (2 mentions)
Diethyl ether, by Merck Group (2 mentions)
Dichloromethane dcm, by Merck Group (2 mentions)
Methanol, by Merck Group (1 mentions)
Dimethylformamide dmf, by Merck Group (1 mentions)
Diisopropylethylamine dipea, by Merck Group (1 mentions)
2 protocols using 1 bis dimethylamino methylene 1h benzotriazolium hexafluorophosphate 3 oxide hbtu
1
Solid-Phase Peptide Synthesis Protocol
2
Peptide Synthesis Using HBTU and Fmoc Chemistry
Check if the same lab product or an alternative is used in the 5 most similar protocols
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1-[bis(dimethylamino)methylene]-1H-benzotriazolium hexafluorophosphate 3-oxide (HBTU) were purchased from GL Biochem (Shanghai, China). Piperidine (PPD) and trifluoroacetic acid (TFA) were purchased from Auspep (Melbourne, Australia). Fmoc-PAL-PEG-PS resins with substitution of 0.18 mmol g -1 were purchased from Applied Biosystems Inc. (Melbourne, Australia). Dimethylformamide (DMF), methanol, diethyl ether, and dichloromethane (DCM) were purchased from Merck (Melbourne, Australia). 3,6-Dioxa-1,8-octanedithiol (DODT), triisopropylsilane (TIPS), diisopropylethylamine (DIPEA) and trifluoromethanesulfonic acid (TFMSA) were pur- chased from Sigma-Aldrich (Sydney, Australia). 2,2-Dipyridyl disulfide (DPDS) was purchased from Fluka (Switzerland). Acetonitrile was purchased from BDH Laboratory Supplies, (Poole, UK). All other reagents were from Sigma-Aldrich (Sydney, Australia). The tricyclohexylphosphine[1,3-bis(2,4,6trimethylphenyl)-4,5-dihydro-imidazol-2-ylidene](benzylidene)ruthenium(II) dichloride (2 nd generation Grubbs' catalyst) was supplied by Aldrich (Sydney, Australia).
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