Whitestar signature

Manufactured by Abbott

Sourced in United States

The WHITESTAR SIGNATURE is a lab equipment product designed for high-performance molecular diagnostic testing. It provides reliable and accurate results for a range of assays, supporting laboratory workflows.

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Lab products found in correlation

Infiniti, by Alcon (1 mentions) Tropicamide, by Alcon (1 mentions) Phenylephrine hydrochloride, by Alcon (1 mentions) Viscoat, by Alcon (1 mentions)

4 protocols using whitestar signature

Comparison of Single- and Triple-Surgery for Glaucoma

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All patients were operated on by a single surgeon (NT) using the same surgical protocol as a previous report.19 (link) All surgeries were performed under local (peribulbar) anesthesia. A 1.6 mm temporal corneal incision at limbus was made, and the handpiece was injected into the anterior chamber. Under the Swan Jacob gonioscopic lens view, the tip of handpiece was inserted through the TM. Approximately 120° arc of the TM and the inner wall of the Schlemm canal was ablated and removed. Patients with phakic eyes underwent cataract surgeries simultaneously. There was no case of lens preservation. A temporal clear cornel incision was made (2.8 mm), and conventional phacoemulsification and IOL implantation (PEA + IOL) were then performed. Phacoemulsification was performed with WHITESTAR SIGNATURE (Abbott Medical Optics, Santa Ana, CA, USA).
We separated the patients into two groups. The 12 patients who underwent only AIT comprised the single-surgery group. The 12 patients who underwent AIT and PEA + IOL simultaneously comprised the triple-surgery group. We compared the IOP and the range of IOP fluctuations between the single-and triple-surgery groups.

Tojo N., Abe S., Miyakoshi M, & Hayashi A. (2017). Comparison of intraocular pressure fluctuations before and after ab interno trabeculectomy in pseudoexfoliation glaucoma patients. Clinical Ophthalmology (Auckland, N.Z.), 11, 1667-1675.

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Phacoemulsification Tip Characterization

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The following 3 phacoemulsification machines were used to perform cataract surgery: Whitestar Signature operated in elliptical mode (Abbott Medical Optics, Inc.), Infiniti (Alcon Laboratories, Inc.) operated in torsional or longitudinal removal modality according to the tip used, and Stellaris (Bausch & Lomb, Inc.) operated in longitudinal mode. An ophthalmic viscosurgical device (OVD) was used during the capsulorhexis and phacoemulsification (hyaluronic acid 1.6%-chondroitin sulfate 4% [Discovisc]) and during IOL insertion (sodium hyaluronate 0.3%-lidocaine 2.0% [Visthesia]).
The chemical composition of different models of phaco tips was accessed using X-ray photoelectron spectroscopy (XPS) and energy-dispersive X-ray spectroscopy (EDS) techniques. Their surface morphology and topography were also analyzed using scanning electron microscopy (SEM) and profilometry.

Cecchini P., D'Aloisio R., Antonuccio M., Turco G., Bondino F., Magnano E., Di Nicola M, & Tognetto D. (2017). Chemical and physical analysis of phaco handpiece tip surfaces before and after cataract surgery. Journal of cataract and refractive surgery, 43(8).

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Cataract Extraction Surgery in Rabbits

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For cataract extraction surgery of the rabbits performed by either YCL or MB, tropicamide (1%; Alcon Laboratories, Fort Worth, TX, United States) and phenylephrine hydrochloride (2.5%; Alcon Laboratories) eye drops were administered 30 minutes before the surgery to achieve mydriasis. A clear corneal incision was made with a 2.8 mm disposable keratome. After viscoelastic material containing sodium chondroitin sulphate and sodium hyaluronate (Viscoat; Alcon Laboratories) was instilled into the anterior chamber, a 5.0 mm diameter continuous curvilinear capsulotomy of the anterior capsule was created. Hydro-dissection was performed using a 27-gauge cannula. The lens was then aspirated and removed with a standard phacoemulsification procedure using the White Star Signature® phacoemulsification system (Abbott Medical Optics, Santa Ana, CA, USA). Subsequently, the corneal incision was sutured with 10/0 nylon suture and the rabbits were left aphakic with an intact posterior capsule for at least one week before TE-EK surgery.

Peh G.S., Ang H.P., Lwin C.N., Adnan K., George B.L., Seah X.Y., Lin S.J., Bhogal M., Liu Y.C., Tan D.T, & Mehta J.S. (2017). Regulatory Compliant Tissue-Engineered Human Corneal Endothelial Grafts Restore Corneal Function of Rabbits with Bullous Keratopathy. Scientific Reports, 7, 14149.

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Lens Capsule Mechanical Characterization

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After creating the FLC or CCC, we completely removed the crystalline lens material using a phacoemulsification device (WHITESTAR Signature; Abbott Medical Optics). Next, we injected viscoelastic material into the capsule and anterior chamber, and we cut the sclera near the equator to approach the crystalline lens from the posterior side. We released the zonule adhesions using surgical scissors and removed the crystalline lens capsule using a dispending spoon. The extracted whole capsule was then immersed in balanced salt solution. Two L-shaped jigs were created and inserted into the capsule openings; these were then pulled at constant speed (30 mm/min) using multipurpose material testing equipment (IMC-90F0; Imoto Machinery Co., Ltd.; Figure 2). We recorded stretch forces and distance over time, and the maximum values in this regard were defined as those that were recorded when the capsule broke. For the irregular CCCs, two jigs were placed and pulled in the specified position as shown in Figure 1 to avoid the direct force at the irregular part of CCC or equatorial part of lens capsule.

Takagi M., Kojima T., Ichikawa K., Tanaka Y., Kato Y., Horai R., Tamaoki A, & Ichikawa K. (2017). Comparison of Maximum Stretch Forces between Femtosecond Laser-Assisted Capsulotomy and Continuous Curvilinear Capsulorhexis. Journal of Ophthalmology, 2017, 3489373.

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