An NPPV ventilator (Respironics V60 Bilevel Ventilator; Philips Respironics, Murrysville, PA, USA) was connected to an ASL 5000 breathing simulator (IngMar Medical Ltd., Pittsburgh, PA, USA) by a standard disposable corrugated circuit (length, 1.8 m). All tests were performed using a dry circuit, and all humidifiers and heat and moisture exchangers were removed. All tests were conducted in October 2018. The average altitude of the test area was 3 to 5 m, daytime temperature was 22 to 25°C, and the relative humidity was 80% to 85%. There was no obvious convection indoors. No people or animals were used in this study, so ethics approval was not required.
Respironics v60 bilevel ventilator
Manufactured by Philips
Sourced in United States
The Respironics V60 Bilevel Ventilator is a medical device designed to provide non-invasive ventilatory support for patients with respiratory insufficiency. It is capable of delivering both inspiratory and expiratory positive airway pressure to assist with breathing.
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Lab products found in correlation
3 protocols using respironics v60 bilevel ventilator
1
Ventilator Performance Testing in Simulator
2
Dry Circuit Ventilation Simulation Study
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This bench study was performed using a dry circuit without a humidifier. First, five passive conditions with zero breathing frequency and zero inspiratory muscle pressure (Pmus) were simulated. A Hamilton C3 ventilator (Hamilton Medical AG, Bonaduz, Switzerland) was linked to the lung simulator without facemask and PEV. The ventilator was calibrated and configured in the volume-controlled ventilation (VCV) mode. Then, it was configured in the pressure-controlled ventilation (PCV) mode. Finally, active conditions with a spontaneous effort were simulated. A Respironics V60 Bilevel Ventilator (Philips, Best, The Netherlands) was also connected to the lung simulator via a 1.8-m-long single-use, single limb, corrugated circuit with facemask and PEV. The V60 ventilator was calibrated and configured in the PSV mode. The ventilator’s parameters were set according to respiratory mechanics profiles: positive end-expiratory pressure (PEEP). The PC and PS levels were adjusted to obtain tidal volumes (VT), achieving 5.0, 7.0, and 10.0 ml/kg body weight outputted by the ventilator using a back-up respiratory rate of 10 breaths/min and maximal duration of the inspiratory phase of 2.0 s. The shorter inspiratory rise time was selected but avoiding overshoot [19 (link), 20 (link)]. The trigger sensitivity and cycling criteria were auto-adjusted in the PSV mode (digital Auto-Trak™) [21 (link)].
3
Simulated Breathing Conditions and Ventilator Settings
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First, four passive breathing conditions were simulated. A Hamilton C3 ventilator (Hamilton Medical AG, Bonaduz, Switzerland), which was linked to the lung simulator without a facemask and PEV. The ventilator was calibrated and configured in the volume-controlled ventilation (VCV) mode. Then, it was configured in the pressure-controlled ventilation (PCV) mode. Finally, active conditions with a spontaneous effort were simulated, and a Respironics V60 Bilevel Ventilator (Philips) was connected to the lung simulator with a facemask and PEV, and the device was configured in the PSV mode. The pressure control (PC) and pressure support (PS) levels were adjusted for the ventilator to obtain tidal volumes (VT) that achieved 5.0, 7.0, and 10.0 mL/kg body weight outputs, and the positive end-expiration pressure (PEEP) was set at 5.0 cmH2O. A backup respiratory rate of 10 breaths/minute was used, and the maximal duration of the inspiratory phase was 2.0 s. A shorter inspiratory rise time was selected, which avoided overshoot.17 (link),18 (link) Trigger sensitivity and cycling criteria were auto-adjusted (digital Auto-Trak™, Philips Respironics).16 (link)
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