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Isoflurane anesthesia

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Isoflurane anesthesia is a laboratory equipment used to administer isoflurane, a volatile anesthetic agent, to animals during scientific procedures. It provides a controlled and regulated delivery of the anesthetic gas to induce and maintain a state of unconsciousness in the subject.

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Coda ht2 tail cuff system, by Kent Scientific (1 mentions)

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Isoflurane (9 citations) SomnoSuite Low-Flow Isoflurane Anesthesia System (2 citations)

3 protocols using isoflurane anesthesia

1

Rat Nerve Injury Surgery Protocol

Cited 1 time
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Using published procedures [31 (link)], 52 rats underwent surgery [23 (link)]. For SNI (n = 29 rats), a portion of the nerve was removed, leaving the sural nerve intact. In sham surgeries (n = 23 rats) nerves were not manipulated. Surgeries used isoflurane anesthesia (Kent Scientific).
Vizcarra V.S., Barber K.R., Franca-Solomon G., Majuta L., Smith A., Langlais P.R., Largent-Milnes T.M., Vanderah T.W, & Riegel A.C. (2022). Targeting 5-HT2A receptors and Kv7 channels in PFC to attenuate chronic neuropathic pain in rats using a spared nerve injury model. Neuroscience letters, 789, 136864.
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2

Rat Nerve Injury Surgery Protocol

Cited 1 time
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Using published procedures [31 (link)], 52 rats underwent surgery [23 (link)]. For SNI (n = 29 rats), a portion of the nerve was removed, leaving the sural nerve intact. In sham surgeries (n = 23 rats) nerves were not manipulated. Surgeries used isoflurane anesthesia (Kent Scientific).
Gern J.E, & Busse W.W. (1999). Association of Rhinovirus Infections with Asthma. Clinical Microbiology Reviews, 12(1), 9-18.
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3

Hypertension Induction in Rats

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Four-month-old rats were treated with 10 mg/kg/day (males weighing 0.38–0.43 kg) and 7.5 mg/kg/day (females weighing 0.23–0.28 kg) L-NAME in drinking water for 1 month, respectively. These doses were established previously (Lai et al., 2021 (link)) such that hypertension is induced without visible effects on normal cage and grooming behavior. Drug exposure was estimated by measuring water consumption in each cage. Hypertension was confirmed by measuring systolic blood pressure at 5, 6, and 9 months of age using the CODA-HT2 tail-cuff system under isoflurane anesthesia (Kent Scientific). Statistical significance was measured by t-test.
Lai A.Y., Bazzigaluppi P., Morrone C.D., Hill M.E., Stefanovic B, & McLaurin J. (2022). Compromised Cortical-Hippocampal Network Function From Transient Hypertension: Linking Mid-Life Hypertension to Late Life Dementia Risk. Frontiers in Neuroscience, 16, 897206.
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