Amplicor hiv 1 monitor standard ultrasensitive

Manufactured by Roche

The Amplicor HIV-1 Monitor—Standard/Ultrasensitive is a laboratory diagnostic test used to quantify the amount of human immunodeficiency virus type 1 (HIV-1) ribonucleic acid (RNA) in human plasma samples. The test utilizes polymerase chain reaction (PCR) technology to amplify and detect HIV-1 RNA.

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Lab products found in correlation

Realtime hiv 1 assay, by Abbott (2 mentions) Versant hiv 1 rna 3.0 bdna, by Roche (1 mentions) Cobas ampliprep cobas taqman hiv 1 test, by Abbott (1 mentions) Versant hiv 1 rna 3, by Siemens (1 mentions)

Close spelling variants of this product

Amplicor HIV-1 Monitor (11 citations) Standard Amplicor HIV Monitor (3 citations)

2 protocols using amplicor hiv 1 monitor standard ultrasensitive

Viral Suppression Evaluation in Youth

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Viral suppression rates were only calculated for those youth who were on ART for at least 6 months. Plasma HIV-1 RNA level (VL) and CD4+ count data obtained within the prior 6 months were abstracted from medical records. The minority (approximately 5%) of participants who did not have VL and CD4 evaluations within 6 months of the study had blood collected at the baseline visit for these measurements. Because of the variability in type of VL assay used across the study sites (i.e., Bayer/Siemens Versant HIV-1 RNA 3.0 (bDNA), Roche Amplicor HIV-1 Monitor—Standard/Ultrasensitive, Roche COBAS AmpliPrep/COBAS TaqMan HIV-1 Test, v1.0, 2.0, and Abbott RealTime HIV-1 Assay), the corresponding assay cutoff for the lower limit of VL (LLD) was used. A dichotomous variable to designate virally suppressed (nondetectable) or virally nonsuppressed (detectable) was created.

Kahana S.Y., Jenkins R.A., Bruce D., Fernandez M.I., Hightow-Weidman L.B, & Bauermeister J.A. (2016). Structural Determinants of Antiretroviral Therapy Use, HIV Care Attendance, and Viral Suppression among Adolescents and Young Adults Living with HIV. PLoS ONE, 11(4), e0151106.

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Plasma HIV RNA and CD4+ Cell Count

Cited 1 time

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Plasma HIV RNAandCD4⁺ cell count data obtained within the last 6 months and type of assay were abstracted from medical records. Because of the variability in type of assay used across the study sites (ie, Versant HIV-1 RNA 3.0 [Siemens Diagnostics]; Amplicor HIV-1 Monitor – Standard/Ultrasensitive [F. Hoffmann-La Roche Ltd]; COBAS AmpliPrep/COBAS Taqman HIV-1 Test, versions 1.0 and 2.0 [F. Hoffmann-La Roche Ltd]; and RealTime HIV-1 Assay [Abbott Laboratories]), we used the corresponding assay cutoff for the lower limit of HIV RNA detection (all were <200 copies/mL; see Kahana et al^{11 (link)} for sensitivity analysis) and created a dichotomous variable to differentiate VL− and VL+ participants.

Wilson P.A., Kahana S.Y., Fernandez M.I., Harper G.W., Mayer K., Wilson C.M, & Hightow-Weidman L.B. (2016). Sexual Risk Behavior Among Virologically Detectable Human Immunodeficiency Virus–Infected Young Men Who Have Sex With Men. JAMA pediatrics, 170(2), 125-131.

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