5 channel cardiac phased array receiver coil

Studies were performed on a 1.5-T Achieva scanner with a 5-channel cardiac phased array receiver coil (Phillips, Healthcare). ECG-triggered steady-state free-precession (SSFP) cine sequences were acquired in short axis and 2-, 3-, and 4-chamber views. Native T1 mapping was performed using a 5 s(3 s)3 s modified look-locker inversion recovery (MOLLI) sequence on three short-axes slices [14 (link)]. A gradient (echo planar imaging) and spin-echo multi-echo sequence was applied to acquire native T2 mapping images in three short-axis slices. Ten minutes after injection of 0.15 mmol/kg gadoterate meglumine (Dotarem®, Guerbet), end-diastolic late gadolinium enhancement (LGE) images were acquired using end-diastolic phase-sensitive inversion recovery (PSIR) sequences in short-axis and 2-, 3-, and 4-chamber views. Additional details are given in the Supplementary Material.

CMR was performed using a 1.5 T Achieva scanner equipped with a 5-channel cardiac phased array receiver coil (Philips Healthcare, Best, The Netherlands) in 129 HCM patients. The CMR protocol included late gadolinium enhancement (LGE) imaging using a phase-sensitive inversion recovery (PSIR) sequence. Gadoter acid (Dotarem, Guerbet, Sulzbach, Germany) was administered as bolus injection of 0.2 mmol/kg at a rate of 2.5 mL/s and after ten minutes end-diastolic LGE images were acquired: AVS 1.59 × 1.71 × 8 mm³, RVS 0.97 × 0.98 × 8 mm³, gap 2 mm, 9–10 slices, echo time = 2.40 ms, time to repetition = 5.50 ms, flip angle = 15°. The optimal inversion delay was obtained from a Look-Locker experiment. LGE images were acquired in short-axis orientation covering the entire heart and in two-, three- and four-chamber views.
Measurements were performed by two independent radiologists who were blinded to clinical data. Myocardial contraction fraction was calculated according to Arenja et al. 2017 [17 (link)]. For statistical analysis the amount of LGE and the myocardial contraction fraction (MCF) were determined.