Trisodium citrate na3c6h5o7

Manufactured by Merck Group

Sourced in Germany, United States

Trisodium citrate (Na3C6H5O7) is a chemical compound commonly used as a buffering agent and preservative in various laboratory applications. It is a white, crystalline solid that is soluble in water. Trisodium citrate helps maintain a specific pH level and can be used to stabilize solutions, prevent coagulation, and enhance the shelf life of certain reagents and samples.

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Close spelling variants of this product

Trisodium citrate (Na3C6H5O7 · 2H2O) Trisodium citrate Na3C6H5O7

12 protocols using trisodium citrate na3c6h5o7

Electrochemical Sensing with Graphene Nanoplatelets

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The chemicals
used in this study were alumina substrates obtained from PT. Pridhana
Eka (Bandung, Indonesia), carbon paste was obtained from Dynamo (Stockholm,
Sweden), silver paste (Ag) and dielectric paste were purchased from
SHOEI Chemical Co Ltd. (Osaka, Japan), and graphene nanoplatelets
were purchased from Johnson Matthey PLC (London, England). Silver
nitrate/AgNO₃ (≥99.0%) was purchased from Sigma-Aldrich
(Germany). Trisodium citrate/Na₃C₆H₅O₇, dimethylformamide (DMF) (99.8%), potassium chloride/KCl
(≥99.5%), sodium chloride, potassium hexacyanoferrate (II)/K₄[Fe(CN)₆], potassium hexacyanoferrate (III)/K₃[Fe(CN)₆] (≥99%), potassium hydrogen phosphate/K₂HPO₄ (≥99.99%), potassium dihydrogen phosphate/KH₂PO₄ (≥99.5%), sodium hydroxide/NaOH, Rhodamine
B/C₂₈H₃₁C_lN₂O₃, sucrose/C₁₂H₂₂O₁₁ (≥99.5%),
monosodium glutamate/C₅H₈NO₄Na, and
sodium benzoate/C₇H₅NaO₂ were obtained
from Merck (Germany). All reagents used in this work were of analytical
grade and were used without further purification. All solutions were
prepared using DI water with a resistivity of >18 MΩ. Traditional
crackers were purchased from a local market.

Kartika A.E., Setiyanto H., Manurung R.V., Jenie S.N, & Saraswaty V. (2021). Silver Nanoparticles Coupled with Graphene Nanoplatelets Modified Screen-Printed Carbon Electrodes for Rhodamine B Detection in Food Products. ACS Omega, 6(47), 31477-31484.

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Pharmaceutical Compound Characterization

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Pure powder of IBU, PXM, LYS, ARG, and GlucN purchased from Zahravi Pharmaceutical Company (Iran); potassium dihydrogen phosphate (K₂HPO₄), sodium hydroxide (NaOH), sodium chloride (NaCl), hydrochloric acid (HCl), citric acid (C₆H₈O₇), and trisodium citrate (Na₃C₆H₅O₇) were obtained from Merck (Darmstadt, Germany). Double distilled water was used during the study.

Valizadeh H., Mahdinloo S., Zakeri N., Sarfraz M., Nezafat S, & Zakeri-Milani P. (2022). Investigating the Effect of Basic Amino Acids and Glucosamine on the Solubility of Ibuprofen and Piroxicam. Advanced Pharmaceutical Bulletin, 13(3), 532-538.

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Synthesis of Tin Sulfide Nanomaterials

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Stannous chloride (SnCl₄·5H₂O, AR, purity 99.0%, Sigma-Aldrich, St. Louis, MO, USA) and thioacetamide (C₂H₅NS, AR, purity ≥ 99%, Sigma-Aldrich, St. Louis, MO, USA) were used as Sn and S precursors, respectively. Trisodium citrate (Na₃C₆H₅O₇, AR, purity 99.9%, Sigma-Aldrich, St. Louis, MO, USA) was used as chelating agent. These compounds were utilized as supplied without additional purification and stored in a humidity-controlled desiccator.

Gedi S., Alhammadi S., Noh J., Minnam Reddy V.R., Park H., Rabie A.M., Shim J.J., Kang D, & Kim W.K. (2022). SnS2 Nanoparticles and Thin Film for Application as an Adsorbent and Photovoltaic Buffer. Nanomaterials, 12(2), 282.

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Graphene-based Colorimetric Biosensor

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Tetrachloroauric (III) acid trihydrate (HAuCl₄ 3H₂O, Sigma-Aldrich, St. Louis, MO, USA), trisodium citrate (Na₃C₆H₅O₇, Sigma-Aldrich, St. Louis, MO, USA), and GO (Graphene Supermarket, Calverton, NY, USA) were used as purchased. Bst DNA polymerase, 10X of ThermoPol buffer, 100 mM magnesium sulfate (MgSO₄), and 10 mM dNTP were obtained from New England BioLabs (Ipswich, MA, USA). SYBR green I fluorescent nucleic acid was purchased from LONZA (Rockland, ME, USA). Ultrapure water was used throughout this study.

Kim J.W., Park K.W., Kim M., Lee K.K, & Lee C.S. (2022). Highly Specific Loop-Mediated Isothermal Amplification Using Graphene Oxide–Gold Nanoparticles Nanocomposite for Foot-and-Mouth Disease Virus Detection. Nanomaterials, 12(2), 264.

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Synthesis of Gold Nanoparticles

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Graphite flakes, sodium nitrate (NaNO₃), sulphuric acid (H₂SO₄, 98% w/w), potassium permanganate (KMNO₄), hydrogen peroxide (H₂O₂, 30% w/w), chloroauric acid (HAuCl₄), tannic acid (C₇₆H₅₂O₄₆) and trisodium citrate (Na₃C₆H₅O₇) were all purchased from Sigma Aldrich (Dorset, UK). Each of the chemicals were used as purchased without additional purification. Ultrapure water was used in all the experiments.

Akere T.H., de Medeiros A.M., Martinez D.S., Ibrahim B., Ali-Boucetta H, & Valsami-Jones E. (2022). Synthesis and Characterisation of a Graphene Oxide-Gold Nanohybrid for Use as Test Material. Nanomaterials, 13(1), 33.

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Electrochemical Silver-Zinc Antimicrobial Process

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BBR chloride (pharmaceutical primary standard) and trisodium citrate (Na₃C₆H₅O₇, purity > 99%) were purchased from Sigma Aldrich. Glycerol was supplied by Fisher Scientific (purity > 99%). Nutrient broth and nutrient agar were provided by Titan Biotech, India. Bi-distilled water through a Milli-Q® system was used.
Two bulk silver bars (99.999% purity) and two bulk zinc bars with dimensions (L × W × T) of 150 × 10 × 0.5 mm were used as electrodes for the electrochemical process.
Two bacterial strains, namely, MRSA (Gram-positive bacteria) and S. enteritidis (Gram-negative bacteria) were provided by the Department of Bacteriology, National Institute of Hygiene and Epidemiology, Vietnam.

Nguyen H.T., Pham T.N., Le L.T., Nguyen T.K., Le A.T., Huy T.Q, & Thu Nguyen T.T. (2023). Complexes of Ag and ZnO nanoparticles with BBR for enhancement of gastrointestinal antibacterial activity through the impacts of size and composition. RSC Advances, 13(9), 6027-6037.

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Synthesis of Gold Nanoparticles

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Trisodium citrate (Na₃C₆H₅O₇), L-cysteine (C₃H₇NO₂S) and tetra-chloroauric (III) trihydrate (HAuCl₄⋅3H₂O) with purity of 99% were purchased from Sigma-Aldrich.

Ou T.Y., Lo C.F., Kuo K.Y., Lin Y.P., Chen S.Y, & Chen C.Y. (2022). Visual Cu2+ Detection of Gold-Nanoparticle Probes and its Employment for Cu2+ Tracing in Circuit System. Nanoscale Research Letters, 17, 104.

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Scalable Synthesis of Monodisperse Gold Nanoparticles

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The Au NPs were synthesized following the protocol of Bastús et al. (2011 (link)) First of all, Au NPs seeds were synthesized. In the next step the seeds were continuously grown to bigger particles; in this work Au NPs with 25 nm sizes are used. For the seed synthesis 150 ml aqueous solution of trisodium citrate (Na₃C₆H₅O₇) (2.2 mM) (Sigma Aldrich, Germany) was boiled for 15 min. Then 1 ml of HAuCl₄-solution (25 mM) (Sigma Aldrich, Germany) is injected at once. The color of the solution was changed from yellow to bluish-gray and then finally to soft pink within 10 min. For growing of bigger sized particles the solution was cooled down to a temperature of 90°C. Into that solution 1 ml sodium citrate (60 mM) and 1 ml of a HAuCl₄-solution (25 mM) was injected. After 30 min the reaction was completed and again 1 ml of a HAuCl₄-solution (25 mM) was added. Thirty minutes later the solution was diluted by taking out 27.7 ml of the Au NP solution and adding 27.6 ml of water.

Yesildag C., Ouyang Z., Zhang Z, & Lensen M.C. (2019). Micro-Patterning of PEG-Based Hydrogels With Gold Nanoparticles Using a Reactive Micro-Contact-Printing Approach. Frontiers in Chemistry, 6, 667.

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Synthesis and Characterization of Gold Nanostars

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Chloroauric acid (HAuCl₄), L-ascorbic acid, silver nitrate (AgNO₃, 99.8%) hydrochloric acid (HCl), and trisodium citrate (Na₃C₆H₅O₇) were purchased from Sigma-Aldrich. Milli-Q deionized (DI) water was used throughout the experiment. The morphology of nanostars was characterized by analysis FEI Tecnai G2 Twin transmission electron microscope, and HAADF STEM images and EDS maps were acquired using Aberration Corrected STEM-Thermo Fisher Titan 80–300. UV-vis spectra were recorded using a Shimadzu UV-3600i spectrometer with cuvettes of 1 cm path length at room temperature.

Atta S., Watcharawittayakul T, & Vo-Dinh T. (2022). Ultra-high SERS Detection of Consumable Coloring Agents Using Plasmonic Gold Nanostars with High Aspect-ratio Spikes. The Analyst, 147(14), 3340-3349.

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Synthesis and Characterization of Nanoparticles

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Silver nitrate (AgNO₃), silver chloride (AgCl), PVP K-30 (polyvinyl pyrrolidone), sodium borohydride (NaBH₄, 96%), hydrogen peroxide (H₂O₂, 30 wt%), and tri-sodium citrate (Na₃C₆H₅O₇) were purchased from Sigma-Aldrich (Canada). Cysteine (Cys), aspartic acid (Asp), arginine (Arg), glucose (Glu), phenylalanine, tyrosine, methionine, proline, and glycine, were obtained from Merck (Germany). The standard solutions of Na⁺, K⁺, Zn²⁺, Mg²⁺, and Ca²⁺ were provided by a Chem Lab Company (Zedelgem, Belgium). DPX was provided by Sobhan Darou Company. Glass fiber papers were supplied from Schleicher & Schuell GmbH, Germany (Ref. No. 10 370 55 and Lot No. FL 091-1). Paraffin was prepared from a local market.

Bahavarnia F., Kohansal F, & Hasanzadeh M. (2024). One-drop chemosensing of dapoxetine hydrochloride using opto-analysis by multi-channel μPAD decorated silver nanoparticles: introducing a paper-based microfluidic portable device/sensor toward naked-eye pharmaceutical analysis by lab-on-paper technology. RSC Advances, 14(4), 2610-2620.

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