Terameprocol (purity of 99.4%) was obtained from Erimos Pharmaceuticals (Houston, TX). Sorafenib-methyl-d3 was purchased from Toronto Research Chemicals (Toronto, ON). HPLC grade acetonitrile, methanol, and formic acid were purchased from EMD Chemical Inc. (Billerica, MA). Deionized water was obtained from the Millipore Milli-Q-UF filtration system (Milford, MA). All other chemicals were of molecular biological grade or higher and were obtained from Sigma–Aldrich (St. Louis, MO). Drug-free human serum, sodium heparin human plasma, and potassium EDTA human plasma were purchased from Biological Specialty Company (Colmar, PA, USA).
Sorafenib methyl d3
Manufactured by LGC
Sourced in Canada
Sorafenib-methyl-d3 is a stable isotope-labeled compound used as an analytical standard in research applications. It serves as a reference material for the identification and quantification of sorafenib, a drug used in the treatment of certain types of cancer, in various analytical procedures.
Automatically generated - may contain errors
2 protocols using sorafenib methyl d3
1
Quantitative Bioanalysis of Terameprocol
2
Simultaneous Quantification of Imatinib and Metabolites
Check if the same lab product or an alternative is used in the 5 most similar protocols
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, N-desmethylimatinib and imatinib-d8 (internal standard) were gifts from Novartis (Basel, Switzerland). Midazolam, dextromethorphan, dextrorphan, and all biochemicals were obtained from Sigma-Aldrich (Castle Hill, NSW, Australia). Sorafenibmethyl-d3 and 6-hydroxypaclitaxel were purchased from Toronto Research Chemicals (North York, ON, Canada) and 1'-hydroxyMidazolam was from Cerilliant (Round Rock, TX, USA).
HPLC grade solvents were from LabScan (Lomb Scientific, Taren Point, NSW, Australia), and analytical grade reagents were from Ajax Chemicals (Sydney, NSW, Australia).
HPLC grade solvents were from LabScan (Lomb Scientific, Taren Point, NSW, Australia), and analytical grade reagents were from Ajax Chemicals (Sydney, NSW, Australia).
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