Cantharidic acid

Manufactured by Santa Cruz Biotechnology

Cantharidic acid is a chemical compound produced by Santa Cruz Biotechnology. It is a naturally occurring substance with potential applications in various research fields. The core function of cantharidic acid is to serve as a research tool for scientific investigation, but its specific intended uses are not provided in this factual, unbiased description.

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Lab products found in correlation

Orthovanadate, by Merck Group (1 mentions) Opti mem 1, by Thermo Fisher Scientific (1 mentions) Nsc87877, by Merck Group (1 mentions) Rpmi 1640, by Thermo Fisher Scientific (1 mentions) Poly l lysine (pll), by Merck Group (1 mentions) Bca protein assay kit, by Thermo Fisher Scientific (1 mentions) Cypermethrin, by Santa Cruz Biotechnology (1 mentions) Okadaic acid, by Merck Group (1 mentions)

2 protocols using cantharidic acid

Protein Assay and Phosphatase Inhibition

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RPMI 1640 and Opti-MEM I were purchased from Invitrogen. Poly-L-lysine was purchased from Sigma. SEE was purchased from Toxin Technology. The BCA Protein Assay Kit was purchased from Pierce Biotechnology. Pervanadate was prepared by mixing orthovanadate (Sigma) and H₂O₂ (Sigma) at a 1:1 ratio and was used at a final concentration of 50 μM. NSC-87877 was purchased from Millipore. Cantharidic acid was obtained from Santa Cruz Biotechnology.

Azoulay-Alfaguter I., Strazza M., Peled M., Novak H.K., Muller J., Dustin M.L, & Mor A. (2017). The tyrosine phosphatase SHP-1 promotes T cell adhesion by activating the adaptor protein CrkII in the immunological synapse. Science signaling, 10(491), eaal2880.

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Neuroprotective Assay with 6-OHDA

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SH-SY5Y cells were pretreated with 200 nM Cantharidic acid (Santa Cruz Biotechnology), 0.2 nM Cypermethrin (Santa Cruz Biotechnology), or 0.5 nM Okadaic acid (Sigma-Aldrich) for 30 min and treated along with 50 μM 6-OHDA for 8 h 30 min. The cell lysates were subjected to Western blot analysis.

Kim H., Oh J.Y., Choi S.L., Nam Y.J., Jo A., Kwon A., Shin E.Y., Kim E.G, & Kim H.K. (2016). Down-regulation of p21-activated serine/threonine kinase 1 is involved in loss of mesencephalic dopamine neurons. Molecular Brain, 9, 45.

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