Cobalt 2 fluoride tetrahydrate

Manufactured by Merck Group

Sourced in Germany

Cobalt(II) fluoride tetrahydrate is an inorganic chemical compound with the formula CoF2·4H2O. It is a pink crystalline solid that is readily soluble in water. The compound is primarily used as a laboratory reagent and in the production of other cobalt-containing compounds.

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2 protocols using cobalt 2 fluoride tetrahydrate

Reagents and Solutions for Antioxidant Assays

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Berberine hydrochloride (B3251, Sigma) stock solution was dissolved in DMSO (D8418, Sigma), working concentrations were prepared in Hank’s balanced salt solution (HBSS, 14025, Invitrogen), with DMSO below 1%. 2,2-azobis-(2-methylpropionamidine) dihydrochloride (AAPH, 440914), 6-hydroxy-2,5,7,8- tetramethylchroman-2-carboxylic acid (Trolox, 238813), cobalt(II) fluoride tetrahydrate (399876), dextran (average molecular weight 464,000) (31392), fluorescein sodium salt (F6377), gallic acid (G7384), luminol (123072), phorbol12-myristate-13acetate (PMA) (P8139), and zymosan particles (Z4250) were purchased from Sigma-Aldrich (Germany). Horseradish peroxidase (HRP, 77332) was purchased from Merck (Darmstadt, Germany). Phosphate buffered saline (PBS) contained 136.9 mmol/l NaCl, 2.7 mmol/l KCl, 8.1 mmol/l Na₂HPO₄, 1.5 mmol/l KH₂PO₄, 1.8 mmol/l CaCl₂ and 0.5 mmol/l MgCl₂, pH 7.4.

KASSAB R.B., VASICEK O., CIZ M., LOJEK A, & PERECKO T. (2018). The effects of berberine on reactive oxygen species production in human neutrophils and in cell-free assays. Interdisciplinary Toxicology, 10(2), 61-65.

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Antioxidant Capacity Measurement Protocol

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2,2′-azobis (2-amidino-propane) dihydrochloride (AAPH), 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (Trolox), fluorescein disodium salt, cobalt (II) fluoride tetrahydrate and gallic acid were obtained from Sigma–Aldrich (Steinheim, Germany). Picollinic acid was purchased from Fluka (Deisenhofen, Germany). All other solvents used were of analytical grade and obtained from local producers.

Argirova M., Guncheva M., Momekov G., Cherneva E., Mihaylova R., Rangelov M., Todorova N., Denev P., Anichina K., Mavrova A, & Yancheva D. (2022). Modulation Effect on Tubulin Polymerization, Cytotoxicity and Antioxidant Activity of 1H-Benzimidazole-2-Yl Hydrazones. Molecules, 28(1), 291.

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