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2 2 azoisobutyronitrile aibn

Manufactured by Merck Group
Sourced in United States

2,2′-Azoisobutyronitrile (AIBN) is a chemical compound used as an initiator in free radical polymerization. It decomposes to generate free radicals that can then initiate the polymerization of various monomers.

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2 protocols using 2 2 azoisobutyronitrile aibn

1

Synthesis and Characterization of Glycidyl Methacrylate and N,N-Diethylacrylamide Copolymers

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Glycidyl methacrylate and N,N-diethylacrylamide (both from Sigma-Aldrich, St. Louis, MO, USA) were freshly distilled under reduced pressure prior to use. 2,2′-Azoisobutyronitrile (AIBN, 98%, Sigma-Aldrich, St. Louis, MO, USA) was recrystallized from hexane and methanol twice, respectively. Tetrahydrofuran (THF, >99%, Molar Chemicals, Halásztelek, Hungary) was refluxed over LiAlH4, distilled, and was kept under nitrogen until its use. Diethyl ether and methanol (>99%, Molar Chemicals, Halásztelek, Hungary), PBS (pH = 7.4) and phosphate buffers (pH = 6; 7; 7.8; 8; 9 both from Sigma-Aldrich, St. Louis, MO, USA) were used without further purification. α-Chymotrypsin and N-benzoyl-L-tyrosine ethyl ester (BTEE, 99%) were purchased from Sigma-Aldrich and were used as received.
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2

Synthesis and Characterization of Biodegradable Polymers

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(3s)-cis-3,6-dimethyl-1,4-Dioxane-2,5-dione (L-lactide) was purchased from SigmaAldrich Inc. (St. Louis, MO) and purified by recrystallization from toluene. Stannous 2ethylhexanoate (Sn(Oct)2) and 2-hydroxyethyl methacrylate (HEMA) were purchased from Sigma-Aldrich Inc. and distilled under reduced pressure before use. 1,4-Dioxane (99%) was purchased from Aldrich Chemical (Milwaukee, WI) and dehydrated with calcium chloride. 2,2’-Azoisobutyronitrile (AIBN) was purchased from Sigma-Aldrich Inc. and recrystallized from ethanol. PLLA (inherent viscosity 1.6 dL/g) was purchased from Boehringer Ingelheim (Ingelheim, Germany). Poly(ethylene glycol) monomethyl ether methacrylate (PEGMA), FITC labeled BSA, 3-aminopropyltriethoxysilane (APTS), 3-(Trimethoxysilyl)propyl methacrylate (TMSPMA), Ncetyltrimethylammonium bromide (CTAB), tetraethyl orthosilicate (TEOS), 1,3,5trimethylbenzene (TMB) and ammonium hydroxide, polyethyleneimine (PEI, Mw 800 Da and 25 kDa), poly(ethylene glycol) (PEG, Mw 2000, 5000, 10000, and 20000 Da), and hyperbranched bis-MPA polyester (H20: 16 hydroxyls, H30: 32 hydroxyls, and H40: 64 hydroxyls) were purchased from Sigma–Aldrich Inc. and used without further treatment.
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