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Fk506 tac

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FK506 (TAC) is a chemical compound used as a laboratory reagent. It functions as an immunosuppressant that inhibits the activity of calcineurin, a protein phosphatase essential for T-cell activation.

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Lab products found in correlation

Voyager detm str system, by Thermo Fisher Scientific (2 mentions) S4700 high resolution scanning electron microscope, by Hitachi (2 mentions) Freezone 2, by Thermo Fisher Scientific (2 mentions)

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FK506 (28 citations)

2 protocols using fk506 tac

1

Synthesis and Characterization of Poly(Lactide) MPs

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d,l-Lactide was purchased from TCI America, recrystallized three times in toluene, and stored at −30°C in a glove box prior to use. (BDI-EI)ZnN(TMS)2 was prepared by following reported procedures (Chamberlain et al., 2001 (link)). FK506 (TAC) (Cayman Chemical) was used as received. All other chemicals were obtained from Sigma-Aldrich and used as received unless otherwise noted. High-performance liquid chromatography (HPLC) analysis was performed on a System Gold system (Beckman Coulter). Infrared spectra were recorded on a PerkinElmer 100 serial Fourier transform infrared spectroscopy (FT-IR) spectrophotometer. MALDI-TOF MS spectra were collected on an Applied Biosystems Voyager-DETM STR system. The sizes and polydispersities of MPs were determined on a ZetaPALS dynamic light-scattering detector. The ζ potential of freshly prepared MPs was evaluated by Malvern Zetasizer. Lyophilization of MPs was completed on a benchtop lyophilizer (Freezone 2.5, Fisher Scientific. The sizes of MPs were characterized on a Hitachi S4700 high resolution scanning electron microscope.
Azzi J., Yin Q., Uehara M., Ohori S., Tang L., Cai K., Ichimura T., McGrath M., Maarouf O., Kefaloyianni E., Loughhead S., Petr J., Sun Q., Kwon M., Tullius S., von Andrian U.H., Cheng J, & Abdi R. (2016). Targeted Delivery of Immunomodulators to Lymph Nodes. Cell reports, 15(6), 1202-1213.
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2

Synthesis and Characterization of Poly(Lactide) MPs

Check if the same lab product or an alternative is used in the 5 most similar protocols
d,l-Lactide was purchased from TCI America, recrystallized three times in toluene, and stored at −30°C in a glove box prior to use. (BDI-EI)ZnN(TMS)2 was prepared by following reported procedures (Chamberlain et al., 2001 (link)). FK506 (TAC) (Cayman Chemical) was used as received. All other chemicals were obtained from Sigma-Aldrich and used as received unless otherwise noted. High-performance liquid chromatography (HPLC) analysis was performed on a System Gold system (Beckman Coulter). Infrared spectra were recorded on a PerkinElmer 100 serial Fourier transform infrared spectroscopy (FT-IR) spectrophotometer. MALDI-TOF MS spectra were collected on an Applied Biosystems Voyager-DETM STR system. The sizes and polydispersities of MPs were determined on a ZetaPALS dynamic light-scattering detector. The ζ potential of freshly prepared MPs was evaluated by Malvern Zetasizer. Lyophilization of MPs was completed on a benchtop lyophilizer (Freezone 2.5, Fisher Scientific. The sizes of MPs were characterized on a Hitachi S4700 high resolution scanning electron microscope.
Azzi J., Yin Q., Uehara M., Ohori S., Tang L., Cai K., Ichimura T., McGrath M., Maarouf O., Kefaloyianni E., Loughhead S., Petr J., Sun Q., Kwon M., Tullius S., von Andrian U.H., Cheng J, & Abdi R. (2016). Targeted Delivery of Immunomodulators to Lymph Nodes. Cell reports, 15(6), 1202-1213.
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