The gross tumor volume (GTV) was delineated on 4DCT expiratory phase with a CT window level of −500 HU and 1600 HU for the center level and width, respectively. The clinical target volume (CTV) was generated by expanding GTV by 2‐mm so as to include any microscopic tumor extension. Then, PTV was created by adding a 3−5 mm margin to CTV to account for setup uncertainties.
23 (link),
24 (link) IMRT plans for HT were retrospectively generated with Planning Station (Accuray) for TomoTherapy HDA. Other settings were as follows: Jaw width was 2.512 cm, pitch value was 0.143, modulation factor was 2.0, and the calculation grid size was 2 × 2 × 2 mm3. The prescribed dose was 42 Gy/4 fractions, which is defined as the dose covering 95% of PTV. The dose constraints of OARs were in accordance with the Japan Clinical Oncology Group (JCOG) 1408 protocol.
25 (link) Although the TPS for Radixact, Precision (Accuray), was not used in this study, we noted that there was not a clear difference between our Planning Station and Precision with respect to the basic beam model, optimizer, and dose calculation.
6 (link) Therefore, our findings using the Planning Station can be extended to that are derived from Precision.
Kosaka T., Takatsu J., Inoue T., Iijima K., Suzuki M., Murakami N, & Shikama N. (2024). Dosimetric evaluation in Helical TomoTherapy for lung SBRT using Monte Carlo‐based independent dose verification software. Journal of Applied Clinical Medical Physics, 25(5), e14305.
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