Grkrk

Manufactured by Proteogenix

Sourced in France

GRKRK is a laboratory device used for the purification and analysis of biomolecules. It utilizes chromatographic techniques to separate and isolate specific components from complex mixtures. The core function of GRKRK is to provide researchers with a reliable and efficient tool for the preparative and analytical processing of biological samples.

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Lab products found in correlation

2 protocols using grkrk

Synthetic Elastin Peptides for Cell Research

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Synthetic elastin peptides (VGVAPG, AGVPGLGVG, GRKRK and TAMRA-AGVPGLGVG) were purchased from Proteogenix. Mouse anti-MMP-2 and anti-uPA antibodies were from Calbiochem. Y27632, blebbistatin, U0126, PD150606, lactose, chondroitin sulphate, nifedipine and EDTA were from Sigma-Aldrich. EGCG was purchased from Enzo Life Sciences. Rabbit anti-Hsp90, anti-cleaved caspase-3, anti-integrin αV, anti-p-ERM, mouse anti-αvβ3 and anti-αvβ5 integrin antibodies were from Ozyme. Rabbit anti-RPSA, anti-MMP-14, anti-calpain1, anti-ROCK2, anti-myosin light chain kinase, mouse anti-RPSA, anti-RhoA, anti-ROCK1 and mouse IgM isotype control antibodies were purchased from Abcam. Rabbit anti-p-LIMK-and goat anti-cofilin and anti-actin were from Santa Cruz. Anti-integrin αvβ3 antibody was purchased from Millipore. Annexin-5 alexa fluor^® 568, CellTrace Calcein Red-Orange, AM and DiOC18³ were from Invitrogen.

Brassart B., Da Silva J., Donet M., Seurat E., Hague F., Terryn C., Velard F., Michel J., Ouadid-Ahidouch H., Monboisse J.C., Hinek A., Maquart F.X., Ramont L, & Brassart-Pasco S. (2019). Tumour cell blebbing and extracellular vesicle shedding: key role of matrikines and ribosomal protein SA. British Journal of Cancer, 120(4), 453-465.

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Hsp90-Targeting Elastin Peptides Modulate

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Synthetic elastin peptides (VGVAPG, AGVPGLGVG and GRKRK) were purchased from Proteogenix (Schiltigheim, France). Matrigel was obtained from Becton-Dickinson (Le Pont de Claix, France). Plasminogen, mouse anti-MMP-2 and anti-uPA antibodies were obtained from Calbiochem (distributed by VWR, Strasbourg, France). Geldanamycin was obtained from Invivogen (Toulouse, France). Radicicol was purchased from Tebu-bio (Le Perray-en-Yvelines, France). Rabbit monoclonal anti-Hsp90 was from Ozyme (Saint Quentin Yvelines, France). Mouse anti-Hsp90 was purchased from Abcam (Paris, France). Goat anti-actin was from Santa Cruz (Heidelberg, Germany). Recombinant Hsp90α protein was from Enzo Life Sciences (Villeurbanne, France).

Donet M., Brassart-Pasco S., Salesse S., Maquart F.X, & Brassart B. (2014). Elastin peptides regulate HT-1080 fibrosarcoma cell migration and invasion through an Hsp90-dependent mechanism. British Journal of Cancer, 111(1), 139-148.

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