Verio mri scanner

Scanning took place in a 3T Siemens Verio MRI scanner at the Functional MRI of the Brain (FMRIB) Centre (University of Oxford), using a 32 channel head coil.

Brain scans were collected using a 3 T Siemens Verio MRI scanner using a manufacturer‐supplied 12‐element matrix head coil at the Clinical Research Imaging Centre (CRIC), the Queen's Medical Research Institute, Edinburgh, UK. After a sagittal localizer, T1‐weighted magnetization‐prepared rapid‐acquisition gradient echo (MPRAGE) MR images were obtained using TR = 2,300 ms, TE = 2.98 ms, and TI = 900 ms, (flip angle = 9, FOV = 256 mm × 256 mm) with an isotropic voxel resolution of 1 mm, parallel to AC‐PC plane.

We included patients with brain lesions in the postcentral gyrus extending into the parietal, temporal and/or pre-/frontal lobe in the same brain hemisphere. Patients with malformations or lesions in the contralateral brain hemisphere were excluded. Cognitive and severe communication deficits were exclusion criteria too. The study was approved by the ethics committee of the University Clinic Leipzig and conducted according to the ethical guidelines of the Declaration of Helsinki. All patients gave written informed consent.
Besides a high-resolution whole-brain 3D standard T1-weighted anatomical image, we used a T2-weighted fluid-attenuated inversion-recovery (FLAIR) image in parallel to better delineate the borders of stroke lesions. Data acquisition was done with a 3 T Bruker MedSpec 100 System (Bruker, Ettlingen, Germany), a 3 T Tim TRIO, or a 3 T VERIO MRI scanner (Siemens, Erlangen, Germany).

A 3T Siemens Verio MRI scanner was used to conduct T1 structural imaging for all study participants with an 8-channel phased-array head coil. Participants had their heads stabilized using cushions, and were given earplugs. A spoiled gradient recalled sequence was used for image acquisition with the following settings: repetition time (TR) = 6.8 ms, echo time (TE) = 3.1 ms, flip angle (FA) = 12 degrees, 196 axial slices with slice thickness = 1 mm, field of view (FOV) = 24 cm × 24 cm, and data matrix = 256 × 256.
The Statistical Parametric Mapping (SPM) software (http://www.fil.ion.ucl.ac.uk/spm/software/spm12/) was used for the preprocessing of the resultant structural images. Default tissue probability maps were initially utilized to separate individual images into GM, white matter, and CSF segments, after which the DARTEL tools from SPM 12 were employed to generate a template for determining nonlinear deformations to convert images of the gray and white matter into the Montreal Neurological Institute (MNI) coordinate space. Spatial smoothing of GM data that were resampled to 2 mm³ voxels was conducted (Gaussian kernel with a full width at a half maximum of 6 mm) (13 (link), 23 (link)).

MRI data was collected using a 3-Tesla Siemens Verio MRI Scanner at the Robert Steiner MR unit at Hammersmith Hospital, London. Functional imaging used a multiband (acceleration factor=2) gradient-echo T2*-weighted echo-planar imaging (EPI) sequence with 42 slices per volume (Repetition time [TR]=2400 ms; Time to Echo [TE]=30 ms; in-plane matrix=64×64; 3 mm isotropic voxels; flip angle=62°; bandwidth=1594 Hz/pixel; 304 volumes; a slice thickness of 3 mm; field of view=192 × 192 mm). The phase encoding direction was from anterior to posterior. Echo spacing was 0.71 ms. There were three dummy scans at the beginning of the scan, which were not included in in our dataset. For structural acquisition, a T1-weighted structural volume was acquired for all participants using a magnetisation prepared rapid gradient echo (MPRAGE) scan (TR=2300 ms; TE=2.28 ms, TI=900 ms, flip angle=9°, field of view= 256 mm, image matrix=256 with 1 mm isotropic voxels; bandwidth=200 Hz/pixel).