Cationic ethylenediamine core poly amidoamine pamam generation 0 dendrimer

Manufactured by Merck Group

Cationic ethylenediamine core-poly(amidoamine) (PAMAM) generation 0 (G0) dendrimer is a type of laboratory equipment used in various scientific applications. It is a branched, tree-like macromolecule with a central core and multiple layers of repeating units known as generations. The G0 dendrimer has a relatively simple structure compared to higher generations. The core function of this dendrimer is to serve as a versatile platform for various research and analytical purposes, such as drug delivery, biosensing, and nanoparticle synthesis.

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Lab products found in correlation

Magnesium sulfate, by Merck Group (2 mentions) Egfp mrna, by TriLink (2 mentions) Ova mrna, by TriLink (2 mentions) Palmitic acid c16 cooh resiquimod r848 anhydrous dichloromethane dcm n n dicyclohexylcarbodiimide dcc, by Merck Group (2 mentions) Anhydrous n n dimethylformamide dmf 4 dimethylaminopyridine dmap hydrochloric acid hcl, by Merck Group (2 mentions) Lipofectamine 2000 l2k, by Thermo Fisher Scientific (2 mentions) Ceramide peg n palmitoyl sphingosine 1 succinyl methoxy polyethylene glycol, by Avanti Polar Lipids (2 mentions)

Close spelling variants of this product

Ethylenediamine (253 citations) PAMAM dendrimer (21 citations)

2 protocols using cationic ethylenediamine core poly amidoamine pamam generation 0 dendrimer

Lipid-Dendrimer Nanocarriers for mRNA Delivery

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EGFP mRNA and OVA mRNA (each modified with pseudouridine and 5-methylcytidine) were purchased from TriLink Biotechnologies. Cationic ethylenediamine core-poly(amidoamine) (PAMAM) generation 0 (G0) dendrimer, palmitic acid (C16–COOH), resiquimod (R848), anhydrous dichloromethane (DCM), N,N′-dicyclohexylcarbodiimide (DCC), anhydrous N,N-dimethylformamide (DMF), 4-dimethylaminopyridine (DMAP), hydrochloric acid (HCl), and magnesium sulfate were purchased from Sigma-Aldrich. Ceramide-PEG (N-palmitoyl-sphingosine-1-(succinyl{methoxy[polyethylene glycol]}) with PEG MW of 2000 was obtained from Avanti Polar Lipids. Lipofectamine 2000 (L2K) was purchased from Invitrogen.

Islam M.A., Rice J., Reesor E., Zope H., Tao W., Lim M., Ding J., Chen Y., Aduluso D., Zetter B.R., Farokhzad O.C, & Shi J. (2020). Adjuvant-pulsed mRNA vaccine nanoparticle for immunoprophylactic and therapeutic tumor suppression in mice. Biomaterials, 266, 120431.

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Lipid-Polymer Hybrid Nanoparticles for mRNA Delivery

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EGFP mRNA and OVA mRNA (each modified with pseudouridine and 5-methylcytidine) were purchased from TriLink Biotechnologies. Cationic ethylenediamine core-poly(amidoamine) (PAMAM) generation 0 (G0) dendrimer, palmitic acid (C16-COOH), resiquimod (R848), anhydrous dichloromethane (DCM), N,N’-dicyclohexylcarbodiimide (DCC), anhydrous N,N-dimethylformamide (DMF), 4-dimethylaminopyridine (DMAP), hydrochloric acid (HCl), and magnesium sulfate were purchased from Sigma-Aldrich. Ceramide-PEG (N-palmitoyl-sphingosine-1-(succinyl{methoxy[polyethylene glycol]}) with PEG MW of 2000 was obtained from Avanti Polar Lipids. Lipofectamine 2000 (L2K) was purchased from Invitrogen.

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