All patients were administered topical anesthesia (C17H28N2O3·HCl eye drops; twice or three times into the conjunctival sac before surgery; Sam Chun Dang Pharm Co., Ltd., Tokyo, Japan) and received LASEK surgery, according to their optimal preoperative corneal refractive power, via a MEL 80™ Excimer Laser System (Carl Zeiss Meditec AG). The central 8-mm surface region of the cornea was infiltrated with 20% alcohol for 15–25 sec under a microscope and the corneal flap was opened. Following incision using an excimer laser, the surgical area was immediately instilled with 0.02 or 0.04% MMC for a duration that was dependent on the patient’s optimal preoperative corneal refractive power: ≤−3.00 diopters (D), 30 sec; between −3.25 and −6.00 D, 60 sec; between −6.25 and −9.00 D, 90 sec; and ≥−9.25 D, 110 sec. The surgical area was rinsed using physiological saline solution. Following resetting of the corneal flap, a soft corneal contact lens was applied.
Mel 80 excimer laser system
Manufactured by Zeiss
Sourced in Germany
The Mel-80 excimer laser system is a medical-grade laser device designed for various ophthalmic applications. It utilizes an excimer laser to generate high-energy ultraviolet light pulses. The core function of the Mel-80 is to precisely ablate corneal tissue, enabling procedures such as photorefractive keratectomy (PRK) and laser-assisted in-situ keratomileusis (LASIK).
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Lab products found in correlation
4 protocols using mel 80 excimer laser system
1
LASEK with Mitomycin-C Protocol
2
Femtosecond Laser-Assisted Corneal Flap Creation
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The VisuMax femtosecond laser system (Carl Zeiss, Oberkochen, Germany) with a pulse of 125 nJ and a frequency of 500 kHz was used to create the corneal stroma flap. The intended diameter and flap thickness were 8.0 mm and 110 mm, respectively. The track and spot distances were set as 3.0 mm for the flap creation and 1.5 mm for turning the flap side cut. The pedicle of the flap was placed on the top. The MEL 80 excimer laser system (Carl Zeiss) was used for stromal ablation. The optical diameter was 6–6.5 mm, and the transition zone was 1.0 mm. Then, the flap was carefully repositioned over the stroma and washed with BSS solution.
3
Femtosecond Laser-Assisted LASIK Procedure
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The same experienced surgeon performed all of the procedures. All flaps, created using the same VisuMax femtosecond laser system, had a superior hinge. After the flap was scanned, a spatula was inserted to lift it. Stromal ablation was performed with a Mel-80 excimer laser system (Carl Zeiss Meditec AG, Germany). The flap diameter was set at 7.5 mm, and 110 µm for the flap thickness. The optical zone varied between 5.75 and 6.25 mm according to the refractive errors and corneal thickness. A bandage contact lens was applied to protect the eye, which was removed the next day.
4
Femtosecond Laser Assisted Corneal Procedures
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We used the VisuMax femtosecond laser system (Carl Zeiss Meditec, Jena, Germany) to perform SMILE and the Mel-80 excimer laser system (Carl Zeiss Meditec AG, Jena, Germany) to perform LASEK. We previously described these procedures in detail [11 (link), 12 (link)].The femtosecond laser settings were as follows: 500 kHz repetition rate, 130 nJ pulse energy, 110 to 120 μm intended cap thickness, 6 to 6.5 mm optical zone, 7.3 to 7.5 mm cap diameter, and a 2 mm side cut at the 12 o’clock position.
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