Desferoxamine mesylate

Manufactured by Merck Group

Desferoxamine mesylate is a pharmaceutical compound used as a chelating agent. It functions by binding and removing excess iron from the body, which can help in the treatment of iron overload conditions.

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Lab products found in correlation

2 protocols using desferoxamine mesylate

Enzymatic Activity Assays for Oxidative Stress

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Antibiotics, 5-aminolevulinic acid hydrochloride (5-ALA), ß-mercaptoethanol, ß-NADH, bovine xanthine oxidase, casein acid hydrolysate, cytochrome c from equine heart, deamino-NADH, desferoxamine mesylate (DFO), diethylenetriamine pentaacetic acid (DTPA), 2,2’-dipyridyl (DIP), ethyl acetate, ferric chloride, ferrous ammonium sulfate, 30% hydrogen peroxide, 8-hydroxyquinoline-5-sulphonic acid, E. coli manganese-containing superoxide dismutase, manganese (II) chloride tetrahydrate, 2-[N-morpholino]ethanesulfonic acid (MES), o-dianisidine dihydrochloride, o-nitrophenyl-ß-D-galactopyranoside (ONPG), potassium ferricyanide, potassium cyanide, tricine, protoporphyrin IX, and xanthine were purchased from Sigma. Ethylenediamine tetraacetic acid (EDTA), guanidine hydrochloride, hydrochloric acid, and 3-(N-morpholino) propane-sulfonic acid (MOPS) were purchased from Fisher Scientific; Coomassie protein assay reagent and albumin standard, from Thermo Scientific; sodium dithionite, from Fluka; and glacial acetic acid, from J.T.Baker.

Martin J.E., Waters L.S., Storz G, & Imlay J.A. (2015). The Escherichia coli Small Protein MntS and Exporter MntP Optimize the Intracellular Concentration of Manganese. PLoS Genetics, 11(3), e1004977.

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Turmeric Curcuminoids Purification and Characterization

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Turmeric (C. longa) and purified curcuminoids (C3 complex^®) were from Sabinsa Corporation and characterized as described in the next section. Nickel-NTA-agarose was from Qiagen. Newborn calf serum was from Atlanta Biologicals and other cell culture reagents were from Thermo Fischer Scientific. Desferoxamine mesylate, disodium EDTA, sodium citrate, silymarin, ferric ammonium citrate, ferric chloride and other metal salts, and dimethylformamide were from Sigma-Aldrich.

Messner D.J., Surrago C., Fiordalisi C., Chung W.Y, & Kowdley K.V. (2017). Isolation and characterization of iron chelators from turmeric (Curcuma longa): selective metal binding by curcuminoids. Biometals : an international journal on the role of metal ions in biology, biochemistry, and medicine, 30(5), 699-708.

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