Absolute dmf

All solvents and chemicals were purchased from commercial suppliers and were used as received. The following chemicals were used without further purification for the synthesis: K₂[PtCl₄] (Assay: 46.69% Pt) (Johnson Matthey, Zurich, Switzerland), glycol chitosan (Assay: 78.2%) (Wako, Osaka, Japan), succinic anhydride (≥99%) (Sigma Aldrich, Steinheim, Germany), acetic anhydride (≥97.0%) (Fisher Scientific, Schwerte, Germany), absolute DMF (99.8%, extra dry, water <50 ppm) (Acros Organics, Geel, Belgium), absolute DMSO (99.7%, extra dry, water <50 ppm) (Acros Organics, Geel, Belgium), triethylamine (99%) (Acros Organics, Geel, Belgium).
Trial Kit Spectra/Por^® 3 (molecular weight cut off (MWCO) = 3.5 kDa) and Spectra/Por^® 7 (MWCO = 1.0 kDa) dialysis tubing was purchased from Carl Roth (Karlsruhe, Germany). All aqueous solutions were performed with Milli-Q water (18.2 MΩ cm, Milli-Q Advantage). Reactions containing platinum complexes were conducted with glass-coated magnetic stirring bars and protected from light.

All chemicals and solvents were purchased from commercial suppliers and were used without further purification. K₂[PtCl₄] was acquired from Johnson Matthey (assay: 46.69% Pt) (Zurich, Switzerland), whereas G2 (20 wt.% in methanol) and G4 PAMAM dendrimers (10 wt.% in methanol) were purchased from Sigma-Aldrich (St. Louis, MO, USA). Additionally, the following chemicals were used as received: succinic anhydride (≥99%) (Sigma-Aldrich, Steinheim, Germany), absolute DMF (99.8%, extra dry, water <50 ppm) (Acros Organics, Geel, Belgium), N-(3-dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride (EDC·HCl) (>98%) (TCI Europe, Zwijndrecht, Belgium), N-hydroxysuccinimide (NHS) (98%) (Sigma-Aldrich, Steinheim, Germany).
Trial Kit Spectra/Por^® 7 (MWCO 1.0 kDa) and Spectra/Por^® 3 (MWCO 3.5 kDa) dialysis tubings were supplied by Carl Roth (Karlsruhe, Germany). Milli-Q water (18.2 MΩ cm, Milli-Q Advantage) was used for aqueous solutions as well as for preparative RP-HPLC purifications. All reactions involving platinum complexes were performed under light protection and with glass-coated magnetic stirring bars.