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59 protocols using ingenia 3t

1

Multimodal Neuroimaging for ROI Delineation

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To ascertain the areas of the regions of concern for setting regions of interest (ROIs), MRI was applied using a 3 T MRI device (3 T Ingenia; Philips Healthcare, Best, The Netherlands) with the following acquisition parameters: three-dimensional mode sampling, TR shortest (6 ms) and TE shortest (2.7 ms), 8° flip angle, 0.9 × 0.9 × 0.9 mm voxel size, 210 slices). Our mobile PET gantry enabled us to reconstruct PET images parallel to the estimated intercommissural line without reslicing. Using this approach, we were able to allocate ROIs on the target regions of the original PET images.
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2

Respiratory-Correlated 4D MRI for Lung Cancer Imaging

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Both T2w and T1w MRI images were acquired on a 3-Tesla MRI scanner (3T Ingenia, Philips Healthcare, Amsterdam, the Netherlands) under an IRB-approved protocol. Six lung cancer patients were scanned in a body mold with both arms up for all MR acquisitions in the coronal direction. In brief, high-resolution (HR: 2x2x2 mm3) T2w RC-4DMRI was acquired using a pulse sequence of a single-shot, turbo spin-echo with echo/repetition time 80/5000-7000 ms and flip angle 90°, together with SENSE (2.0) and partial Fourier (0.7) for acceleration. An MR navigator box was placed at the right diaphragm dome to serve as an internal respiratory surrogate to trigger a prospective RC-4DMRI acquisition. Three respiratory bins were utilized with a narrow acquisition amplitude level (window) and the scanning time was about 5 minutes. More T2w RC-4DMRI acquisition details were described before8 (link).
T1w 3D cine images in BH (HR: 2x2x2 mm3) and FB (LR: 5x5x5 mm3, 2Hz) were acquired using multi-shot, fast turbo field echo with echo/repetition time 1.9/4.2 ms and flip angle 15°, together with SENSE (4 for HR and 6 for LR) and partial Fourier (0.8) approximation. A BH scan took 20 s and the FB scan lasted 40 s at a 2Hz frame rate. The field of view was set the same for T1w and T2w scans, covering the full lungs and liver. More details of BH and FB 3D cine MR acquisition can be found elsewhere17 (link).
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3

Multimodal Neuroimaging Protocol for Cognitive Evaluation

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Structural imaging was acquired in 67 participants, either on a research-dedicated 3 T hybrid PET-MR scanner (SIGNA (TM), GE Healthcare, Chicago, IL) at the CUB Hôpital Erasme (Brussels, Belgium) using whole-brain axial 3D T1 sequence, or on a Discovery MR750w 3 T (GE Medical Systems, Milwaukee, WI, U.S.A.) or 3 T Ingenia (Philips Medical Systems, Best, Netherlands) at Universitair Ziekenhuis Brussel (UZ Brussel) using sagittal 3D T1-weighted (T1w) MR sequence and a sagittal 3D fluid attenuated inversion recovery (FLAIR) sequence. Some patients had already undergone a brain MRI for clinical routine use or for another research protocol. In that case, the scanner used was the 1.5 T Achieva dStream (Philips Medical Systems, Best, The Netherlands) or 3 T Skyra (Siemens Medical Solutions, Pennsylvania, U.S.A.) with sagittal 3D T1-weighted (T1w) MR sequence and a sagittal 3D fluid attenuated inversion recovery (FLAIR) sequence. For one participant, MRI was performed in another hospital using a sagittal 3D T1-weighted (T1w) MR sequence. All MRI scans were performed within 1 year after neuropsychological testing, except for one MCI patient who had the MRI 14 months after neuropsychological testing.
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4

Diffusion Tensor Imaging of Language Tracts

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The magnetic resonance (MR) examinations were performed at a 3T MR system (Philips 3T-Ingenia; Philips medical system) using an eight-element phased array sensitivity encoding head coil.
DTI was performed using a single-shot spin-echo echo-planar-imaging pulse sequence with a diffusion sensitization (b = 1000 seconds/mm2), TR 3000 ms, TE 94 ms, slice thickness between 2.5 mm, no gap between slices, matri × 92 × 88, flip angle 90°. DTI measurements are obtained using either ROI analysis or tractography. The CST and some of the major subcortical tracts involved in the phonologic or semantic loop of language – superior longitudinal fascicle and inferior fronto-occipital were reconstructed, defining for each tract separately, the regions of interest (ROIs) around areas of the WM that all the fibers of each tract must pass through to reach their cortical or subcortical endstations.
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5

Epilepsy Evaluation at Tertiary Hospital in Kenya

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We conducted the study at the pediatric neurology department of the Aga Khan University Hospital (AKUH), in Nairobi, Kenya. AKUH is a tertiary hospital with a cosmopolitan catchment population that includes referrals from other parts of the country. There is no known endemic neurological disease in the immediate catchment population of Nairobi. The pediatric neurology department runs four clinics in a week, each with an approximate attendance of 15–20 patients. Approximately 70% of children seen at these clinics have epilepsy. Over the study period, this service was mostly supported by one neurologist and several pediatricians and pediatric registrars. The hospital has three MRI machines (GE1.5T Signa Excite, in place from 2012–2016; GE 1.5T Signa Explorer from 2016 to date; and Philips 3T Ingenia, in place since 2013 to date). The radiology department is supported by eight consultant radiologists, of whom two are neuroradiologists. The hospital's neurophysiology department has two 21-lead EEG machines and is supported by a neurophysiology team of three.
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6

MRI Acquisition of Structural and Diffusion Data

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Subjects were scanned on a Philips 3 Tesla (T) Intera system (Philips Healthcare, Amsterdam, Netherlands) with a 32-channel head coil at University of Texas McGovern Medical School. During the study, several datasets were corrupted due to scanner equipment failure (n = 8); these subjects were excluded from the present study. In November 2014, the scanner was upgraded to a Philips 3 T Ingenia; as such, we adjust for scanner hardware upgrade in our statistical analyses. The T1-weighted sequence was acquired in the sagittal plane with parameters: TR/TE = 8.07/3.68 ms, flip angle = 6°, acquisition matrix = 256 × 256, FOV = 256 mm, slice thickness = 1 mm, with resultant voxel size = 1 × 1 × 1 mm3. The DTI sequence was acquired using single-shot spin-echo echo planar imaging with parameters: TR/TE = 8700/67 ms, flip angle = 90°, acquisition matrix = 96 × 96, FOV = 240 mm, slice thickness = 2.5 mm, with resultant voxel size = 2.5 × 2.5 × 2.5 mm3. A single non-diffusion weighted volume was acquired (b = 0 s / mm2), along with 32 diffusion-weighted volumes (b = 1000 s / mm2).
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7

MRI Assessment of Intervertebral Disc Degeneration and Regeneration in Rabbits

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Magnetic resonance imaging (MRI) evaluations of rabbits were performed before and 2 wk after puncture to confirm the degeneration as well as 6 wk after transplantation. Rabbits were tranquilized using ketamine (40 mg/kg) and xylazine (3 mg/kg). A localizing midsagittal T2-weighted image was obtained to view the L1-2 through L5-6 using a Philips 3T Ingenia (Philips Healthcare, Best, The Netherlands). Three-mm-thick midsagittal sections were taken using T2-weighted imaging sequences to evaluate signal characteristics within the IVDs. IVD degeneration and regeneration was determined by loss or gain of signal intensity and/or loss of IVD height on the T2-weighted sequence of the disc, respectively. Quantification of IVD height was determined by measuring the distance between the upper and lower vertebral bodies in the sagittal T2-weighted MRI images at the L2-3, L3-4, and L4-5 as previously published.36 (link) NP content was analyzed by measuring the mean signal intensity using Philips DICOM viewer version R3.0 SP3 (Philips Healthcare).
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8

Localizing Epileptic Seizure Origin with ECoG

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In this study we included seven individuals with epilepsy (mean age 28; Table 1). The participants were implanted with subdural ECoG grids and strips (inter-electrode distance 1 cm center-to-center and 2.3 mm exposed surface; Ad-Tech, Racine, USA) to localize the origin epilepsy. They agreed to participate in this study and signed informed consent according to the Declaration of Helsinki (2013). The study was approved by the Medical Ethical Committee of the University Medical Center Utrecht.
The ECoG grids and strips fully or partially covered the hand region of the sensorimotor cortex. The exact location and number of electrodes differed per participant (Figure 1) and depended on the clinical plan to determine the epileptic seizure onset location. Electrodes were localized with a procedure described in Hermes et al. (2010) (link) and Branco et al. (2018) (link), where a post-implantation Computerized Tomography (CT) scan (Philips Tomoscan SR7000, Best, the Netherlands) is co-registered with a pre-implantation T1-weighted anatomical magnetic resonance imaging (MRI) scan (Philips 3T Ingenia or 7T Achieva, Best, the Netherlands; 1 mm isotropic), and displayed on a Freesurfer pial surface (recon-all, http://surfer.nmr.mgh.harvard.edu/).
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9

MRI Imaging Protocol for 3T Ingenia System

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All CMR examinations were performed using a Philips 3 T Ingenia MR system (Philips Healthcare, Best, Netherlands).
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10

Multimodal MRI Imaging Protocols

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iuMR and PMMR examinations were performed according to local institutional protocols on either a 3T Ingenia (Philips Healthcare, Amsterdam, The Netherlands), 3T GE Excite (GE Medical Systems, Milwaukee, USA) or 1.5T Avanto (Siemens, Erlangen, Germany) MRI scanner.
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