Eclipse 10.0 treatment planning system

Manufactured by Agilent Technologies

Sourced in United States

The Eclipse 10.0 treatment planning system is a software solution designed for radiation therapy planning. It provides tools and functionality for the visualization, analysis, and optimization of radiation treatment plans.

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Lab products found in correlation

Brilliance ct big bore oncology configuration, by Philips (2 mentions)

Close spelling variants of this product

Eclipse treatment planning system (191 citations) Eclipse planning system (31 citations) Eclipse 10.0 (7 citations) Eclipse version 10.0 treatment planning system (2 citations)

4 protocols using eclipse 10.0 treatment planning system

IMRT Protocol for Localized Tumor Treatment

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RT was administered with 6 MV photons 5 days per week. The doses per fraction were 1.8–2.0 Gy, and the total dose ranged from 56 to 60 Gy. The IMRT regimen was performed in all radiation treatment plans. None of the patients received further radiation in addition to the session included in the initial planned course. During this time, computed tomography (CT) scans using intravenous and oral contrast agents were obtained for all patients. Images were acquired with the participants in the supine position. All procedures were performed with the Eclipse 10.0 Treatment Planning System (Varian Medical Systems Inc., Palo Alto, CA, USA).
The gross tumor volume (GTV) was defined as the region of the primary tumor along with any related lymph nodes (>1 cm on the short axis) and was determined by the treating radiation oncologist. A 1.5-cm circumferential and 4-cm superior/inferior expansion of this area, including the involved contours of the GTV, was defined as the clinical target volume (CTV). After considering the daily setup error and motion, the planning target volume (PTV) was expanded by 0.5 cm in the radial dimension beyond the CTV to address these issues.

Zhang J., Lv Y., Chen F., Wang X., Zhang L, & Zhang X. (2021). Doses of intensity-modulated radiotherapy and its association with cardiac disease in esophageal cancer patients. Annals of Translational Medicine, 9(2), 166.

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Immobilization and CT Imaging Protocol

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All of the patients were immobilized with a head and upper thoracic thermoplastic mask in a supine position with their arms alongside their bodies. All of the CT datasets were acquired using a helical CT scanner (Philips Brilliance CT Big Bore Oncology Configuration, Cleveland, OH, USA). The CT images were taken at a 5-mm thickness throughout the entire thorax and neck that extending to 10 cm beyond the borders of the tumor. The data were transferred to the Eclipse 10.0 treatment planning system (Varian Medical Systems, Palo Alto, CA, USA) according to the DICOM 3.0 protocol.

Zhang W.Z., Zhai T.T., Lu J.Y., Chen J.Z., Chen Z.J., Li D.R, & Chen C.Z. (2015). Volumetric Modulated Arc Therapy vs. c-IMRT for the Treatment of Upper Thoracic Esophageal Cancer. PLoS ONE, 10(3), e0121385.

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Volumetric Analysis of Tumor Response

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Three simulation CT scans were performed for every patient: before induction chemotherapy, before radiotherapy and the fourth week of radiotherapy. The primary tumor and the metastatic lymph nodes were delineated on simulation CT images according to the MRI and CT fused images. The volume was automatically measured by Eclipse 10.0 treatment planning system (Varian, CA, USA). The definitions of tumor volume were listed as follows: pre-induction chemotherapy gross primary tumor (preIC GTVnx) and lymph node (preIC GTVnd)、post-induction chemotherapy gross primary tumor(postIC GTVnx) and lymph node (postIC GTVnd), gross primary tumor at fourth week of radiotherapy (midRT GTVnx) and lymph node (midRT GTVnd).

Li Y., Zang J., Liu J., Luo S., Wang J., Hou B., Zhao L, & Shi M. (2021). Residual Volume of Lymph Nodes During Chemoradiotherapy Based Nomogram to Predict Survival of Nasopharyngeal Carcinoma Patient Receiving Induction Chemotherapy. Frontiers in Oncology, 11, 739103.

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CT-based Treatment Planning for Patients

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Patients were immobilized in supine position with the head and shoulders encompassed in a thermoplastic shell. Contrast-enhanced CT scan (3mm slice thickness) from the neck to the upper abdomen was obtained using a 16-slice CT scanner (The Philips Brilliance CT Big Bore Oncology Configuration, Cleveland, OH). CT images were then delivered to the Eclipse 10.0 treatment planning system (Varian Medical Systems, Palo Alto, CA) for target volume, OARs contouring and subsequent treatment planning.

Chen J., Guo H., Zhai T., Chang D., Chen Z., Huang R., Zhang W., Lin K., Guo L., Zhou M., Li D., Li D, & Chen C. (2016). Radiation dose escalation by simultaneous modulated accelerated radiotherapy combined with chemotherapy for esophageal cancer: a phase II study. Oncotarget, 7(16), 22711-22719.

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