To fairly assess ACE using experimental film measurements, the MCVC applicator model in the OcB Applicator Modeling module must be verified against the physical MCVC applicator. Additionally, initial film measurements revealed a non‐uniform and slightly lower average dose at the applicator surface compared to TG‐43. To further investigate the origin of the dose variations and verify the applicator library model, micro‐CT (μCT) images were obtained of the MCVC applicator, using a Siemens Inveon™ Hybrid Micro‐PET/CT Scanner (Siemens, Knoxville, TN, USA). The images were used to accurately measure the dimensions and geometry of the applicator, film, and sleeve, which could contribute to deviations in the measured dose from the specified dose. The images had isotropic voxels with a side length of 31μm. Image analysis was performed using ImageJ v1.49 (National Institutes of Health, USA).
Inveon hybrid micro pet ct scanner
Manufactured by Siemens
Sourced in United States
The Inveon™ Hybrid Micro‐PET/CT Scanner is a laboratory equipment product designed to perform Positron Emission Tomography (PET) and Computed Tomography (CT) imaging simultaneously. It combines both imaging modalities into a single integrated system.
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Lab products found in correlation
2 protocols using inveon hybrid micro pet ct scanner
1
Validating MCVC Applicator Dose Measurements
2
In Vivo Bone Formation Evaluation
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hMSCs (1 × 106/cm3) were induced with osteoinduction medium for 7 days in vitro, embedded into 3D PCL scaffolds, followed by implanting subcutaneously into the dorsal surface of 8- to 10-week-old male non-obese diabetic (NSD) mice. The whole mice were subjected to in vivo micro-CT scanning after 4 or 8 weeks of implantation using Inveon hybrid microPET/CT scanner (Siemens). The region of interest (ROI) of the implanted scaffold was defined for analysis in Inveon Research workspace 4.2 (Siemens Healthineers). Mineralization was evaluated by calculating the volume and intensity of mineralized tissue in the ROI.
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