Magnesium stearate

Manufactured by SD Fine Chemicals

Sourced in India

Magnesium stearate is a fine, white, powder-like substance. It is a commonly used lubricant and glidant in the production of pharmaceutical, cosmetic, and food products.

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Lab products found in correlation

8 protocols using magnesium stearate

Formulation and Evaluation of Atenolol

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Atenolol was gift sample from Smruthi Organics Pvt. Ltd., Hyderabad, India. NaCl, mannitol, dicalcium phosphate, magnesium stearate, talc, hydrochloric acid, and sodium hydroxide were purchased from S.D. Fine Chemicals, Mumbai, India. PVP k-30 was purchased from Himedia Laboratories Ltd., Mumbai, India. Cellulose acetate (CA) was a gift sample from AET Pharma, Hyderabad, India. Ethyl cellulose, HPMC K₄M, and dibutyl phthalate (DBP) were gift samples from Dr. Reddy's Laboratories, Hyderabad, India. Acetone, isopropyl alcohol, and poly (ethylene glycol) (PEG)-400 were purchased from Merck Ltd., Hyderabad, India. All chemicals and reagents used were of analytical or pharmacopoeial grade.

Arjun N., Narendar D., Sunitha K., Harika K, & Nagaraj B. (2016). Development, evaluation, and influence of formulation and process variables on in vitro performance of oral elementary osmotic device of atenolol. International Journal of Pharmaceutical Investigation, 6(4), 238-246.

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Preparation and Evaluation of Lansoprazole Capsules

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Lansoprazole and Amoxycillin were received as gift by Sri Pharmacare Powai, Mumbai, India. HPMC K100M, Ethyl cellulose, Sodium starch glycolate, Polyvinyl pyrrolidone K 30, Magnesium stearate, Talc, Microcrystalline cellulose, Isopropyl alcohol, obtained from S.D. fine chemicals, Mumbai. Sodium bicarbonate, citric acid, Magnesium stearate and talc were obtained from Loba Chemical Pvt Ltd (Mumbai, India). All other chemical was purchased from Hi Media, Mumbai. Double distilled water was prepared freshly and used whenever required. All other chemicals used in this study including those stated were of analytical reagent (A.R.) grade.

Singh N., Pandey D.P., Jain N., & Jain S. (2021). Formulation and In Vitro Evaluation of Bilayer Tablets of Lansoprazole and Amoxycillin Trihydrate for the Treatment of Peptic Ulcer. Journal of Drug Delivery and Therapeutics, 11(1), 23-31.

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Abacavir Sulphate Tablet Formulation

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Abacavir sulphate was given as gift sample by KP Labs, Hyderabad. Carbopol 974P, HPMC K4M and Ethyl cellulose was obtained from MerckSpecialities Pvt Ltd, Mumbai, sodium bicarbonate, citric acid, microcrystalline cellulose, talc and magnesium stearate was obtained from SD-Fine Chemicals, Mumbai.

Thatikonda N., Prasad B.S.G., Chinnala K.M., & Nalla A. (2022). FORMULATION AND IN-VITRO CHARACTERIZATION OF ABACAVIR SULPHATE EFFERVESCENT FLOATING TABLETS. YMER Digital, 21(02), 145-157.

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Formulation and Evaluation of Ketorolac Tromethamine Tablets

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Ketorolac tromethamine was gift sample from Dr. Reddy's Laboratories, Ahmadabad, India. Ethyl cellulose (lot no. 02129) was obtained from Central Drug House (P) Ltd, New Delhi, India. Eudragit RS100 was obtained from Evonik Roehm (Germany). Microcrystalline cellulose, magnesium stearate, methanol, and dichloromethane were purchased from S.D. Fine Chemicals (Mumbai, India). All other chemicals were purchased from local sources.

Shahi P., Kumari N, & Pathak K. (2015). Microspheres and tablet in capsule system: A novel chronotherapeutic system of ketorolac tromethamine for site and time specific delivery. International Journal of Pharmaceutical Investigation, 5(3), 161-170.

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Formulation and Evaluation of Solid Dosage Forms

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Methocel K4M (Colorcon Ltd.), Carbopol 974P (Lubrizol), Cremophor EL (Gattefosse), Solutol HS15 (Gattefosse), Transcutol P (Gattefosse), Aerosil 200 (Evonik), Hard gelatin capsules (ACG capsules) were obtained as gift samples. Mannitol, Magnesium stearate, Tween 80, PEG 400 and sodium alginate were purchased from SD Fine Chemicals Ltd. All other reagents and chemicals were of AR grade.

Phadatare A.G., Viswanathan V, & Mukne A. (2014). Novel strategies for optimized delivery of select components of Allium sativum. Pharmacognosy Research, 6(4), 334-340.

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Chewing Gum Formulation and Compression

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MCG’s preparation technology was as follows: powders of lysozyme hydrochloride (Bouwhuis Enthoven B.V., Raalte, The Netherlands), apple taste additive (Kerry Inc., Kuala Lumpur, Malaysia), and sucralose (V.B. Medicare Pvt. Ltd., Karnataka, India) were dry-blended, wetted with ethyl alcohol 96%, then granulated through a sieve and dried at room temperature. The obtained granules were thoroughly mixed with ascorbic acid (Foodchem International Corporation, Shangai, China), Health in Gum^® PWD 01 (Cafosa Gum SA, Barcelona, Spain), and Syloid^® FP244 (Grace GmbH & Co. KG, Worms, Germany), on which the Apple liquid flavour (Kerry Inc., Kuala Lumpur, Malaysia) was previously sprayed. At the last stage, the homogeneous mass of magnesium stearate (S.D. Fine Chemicals Ltd., Mumbai, India) was added to this mixture. Round flat-faced chewing gums with a mass of 1000 mg and a diameter of 13 mm were compressed at a compression force of 7 kN on a laboratory single-punch tablet machine (model HTM-01E, Mariupol Plant of Technological Equipment, Mariupol, Ukraine) [27 (link)].

Maslii Y., Garmanchuk L., Ruban O., Dovbynchuk T., Herbina N., Kasparaviciene G, & Bernatoniene J. (2023). The Study of the Cytotoxicity, Proliferative and Microbiological Activity of the Medicated Chewing Gum with Ascorbic Acid and Lysozyme Hydrochloride Using Different Culture of Cells. Pharmaceutics, 15(7), 1894.

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Sustained-Release Atenolol Formulation

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Atenolol as a gift sample from Vapi Care Pharma Limited, Vapi, Gujarat; Hydroxypropyl methylcellulose K100M, hydroxypropyl methyl cellulose K15M, hydroxypropyl methyl cellulose K4M from Burgeon Pharmaceuticals, Chennai; Carbopol 934P, PVP K-30 from Triveni Chemicals, Vapi, Gujarat; Sodium bicarbonate, Magnesium stearate, talc from SD Fine Chemicals, Mumbai; Citric acid, Spray dried Lactose from Kawarlal and Co., Mumbai.

Siddam H., Kotla N.G., Maddiboyina B., Singh S., Sunnapu O., Kumar A, & Sharma D. (2016). Formulation and evaluation of atenolol floating bioadhesive system using optimized polymer blends. International Journal of Pharmaceutical Investigation, 6(2), 116-122.

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Curcumin-Loaded Polymeric Nanoparticles

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Curcumin was obtained as a gift sample from Konark Herbal and Health Care, Mumbai, India. The reagents including ethyl cellulose were obtained from High Purity Laboratory Chemicals, Mumbai. Polyvinyl alcohol, dichloromethane, methanol, lactose monohydrate, magnesium stearate, triethanolamine, Polyvinyl alcohol, propylene glycol, carbopol 934P and N-methyl-2-pyrrolidone were procured from SD Fine-Chem. Limited, Mumbai. Potassium dihydrogen orthophosphate anhydrous (monobasic), starch and acacia were obtained from Central Drug House (CDH, India). Disodium hydrogen phosphate dihydrate (Na₂HPO₄·2H₂O) and sodium lauryl sulfate were provided by Hi-Media lab. Pvt. Ltd. All other chemicals were of reagent grades and used as procured.

Bhatia M, & Saini M. (2018). Formulation and evaluation of curcumin microsponges for oral and topical drug delivery. Progress in Biomaterials, 7, 239-248.

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