Adult male sd rats

Manufactured by Charles River Laboratories

Sourced in China

Adult male Sprague-Dawley (SD) rats are laboratory animals commonly used in research and testing. They are adult male individuals of the Sprague-Dawley strain, a widely used outbred albino rat model.

Automatically generated - may contain errors

Lab products found in correlation

Sprague dawley rat, by Charles River Laboratories (1 mentions)

Spelling variants of this product

SD rats (86 citations) Male SD rats (29 citations) Adult male rats (5 citations)

7 protocols using adult male sd rats

Heterogeneous Rat Model for HFHSD Study

Check if the same lab product or an alternative is used in the 5 most similar protocols

Adult male SD rats (250–265g on arrival, Charles River Laboratories, Wilmington, MA) were selected for documented BW heterogeneity during HFHSD maintenance^{1 (link),2 (link)}. Upon arrival, rats were individually housed in wire-bottomed hanging cages under 12-h light/12-h dark cycle with ad libitum access to pelleted chow (Purina 5001, St. Louis, MO) and water for at least one week. All procedures conformed to the institutional standards of the University of Pennsylvania IACUC and were consistent with the NIH Guide for the Care and Use of Laboratory Animals.

Wald H.S, & Grill H.J. (2019). Individual differences in behavioral responses to palatable food or to CCK predict subsequent diet-induced obesity. Obesity (Silver Spring, Md.), 27(6), 943-949.

+ Open protocol

+ Expand

Heterogeneous Rat Model for HFHSD Study

Check if the same lab product or an alternative is used in the 5 most similar protocols

Wald H.S, & Grill H.J. (2019). Individual differences in behavioral responses to palatable food or to CCK predict subsequent diet-induced obesity. Obesity (Silver Spring, Md.), 27(6), 943-949.

+ Open protocol

+ Expand

Sprague Dawley Rat Physiological Study

Check if the same lab product or an alternative is used in the 5 most similar protocols

This study was carried out on newborn Sprague Dawley (SD) rats (10 days old) and adult male SD rats weighing 240–310 g (Charles River Laboratories, Beijing, China). The rats were housed in a specific pathogen-free environment and given a standard diet and drinking water ad libitum. Animal surgical procedures were approved by the Committee of Laboratory Animals of Nantong Rich Hospital (CIR20201006), and performed in accordance with the Guideline for the Care and Use of Laboratory Animals.

Duan Q, & Wu J. (2023). Dihydroartemisinin ameliorates cerebral I/R injury in rats via regulating VWF and autophagy-mediated SIRT1/FOXO1 pathway. Open Medicine, 18(1), 20230698.

+ Open protocol

+ Expand

Rat Care and Handling Protocol

Check if the same lab product or an alternative is used in the 5 most similar protocols

Adult male SD rats (9 weeks, n=22) were purchased from Charles River Laboratories (Raleigh, NC) and housed 2 per cage with a 10-h light/14-h dark cycle, 22 °C environment. All testing was conducted during the light cycle. They were fed enough food pellets to maintain body weights at 300–350 g and had free access to water. Any procedures that caused potential pain or stress for the animals were conducted while under isoflurane anesthesia. Adequate depth of anesthesia was determined by response to a paw pinch and by monitoring respiration. Animals were housed in facilities that are fully accredited by the Association for Assessment and Accreditation of Laboratory Animal Care International. The use of rats was approved by the Institutional Care and Use Committee of the Universities of Arkansas for Medical Sciences in accordance with the “Guide for the Care and Use of Laboratory Animals” (National Research Council 2011).

McClenahan S.J., Kormos C.M., Gunnell M., Hambuchen M.D., Lamb P., Carroll F.I., Lewin A.H., Peterson E.C, & Owens S.M. (2019). Design, Synthesis and Biological Evaluation of a Bi-specific Vaccine Against α-Pyrrolidinovalerophenone (α-PVP) and 3,4-Methylenedioxypyrovalerone (MDPV) in Rats. Vaccine, 38(2), 336-344.

+ Open protocol

+ Expand

Controlled Environment for SD Rat Study

Check if the same lab product or an alternative is used in the 5 most similar protocols

Adult male SD rats (200–220 g) were purchased from Beijing Vital River Laboratory Animal Technology Co., Ltd. (Beijing, China; License No. SCXK (Jing) 2016-0006) and kept under specific pathogen-free conditions. A controlled environment of 20 ± 2 °C, 45–50% humidity, and a 12-h light/dark cycle was maintained throughout the study. All animal protocols were approved and conducted according to recommendations from the Research Subcommittee of Hebei Medical University on Animal Care and Use and the Chinese Council on Animal Care.

Chen H.X., Liang F.C., Gu P., Xu B.L., Xu H.J., Wang W.T., Hou J.Y., Xie D.X., Chai X.Q, & An S.J. (2020). Exosomes derived from mesenchymal stem cells repair a Parkinson’s disease model by inducing autophagy. Cell Death & Disease, 11(4), 288.

+ Open protocol

+ Expand

Chronic Restraint Stress and SGKL Treatment in Rats

Check if the same lab product or an alternative is used in the 5 most similar protocols

Adult male SD rats (6–8 weeks of age) weighing 180–200 g were purchased from Vital River Laboratory Animal Technology Co. Ltd (Beijing, China). The rats were randomly divided into three groups: control group (n = 8) containing rats not exposed to any stress; CRS group (n = 8) exposed to CRS; and SGKL group (n = 8) exposed to CRS on SGKL treatment. The rats were subjected to 6 h of restraint stress in a mineral water bottle every day at random times after 1‐week habituation to the environment. CRS modeling was performed continually for 4 weeks. After CRS modeling each day, SGKL treatment was immediately administered at the dose of 0.63 g/kg/day. The treatment was continued for 4 weeks. Behavioral tests and weighing were performed after modeling. All animal works were conducted with the approval of the Ethics Committee of China‐Japan Friendship Hospital (zryhyy21‐20‐09‐9).

Li J., Li Y., Duan W., Zhao Z., Yang L., Wei W., Li J., Li Y., Yu Y., Dai B, & Guo R. (2022). Shugan granule contributes to the improvement of depression‐like behaviors in chronic restraint stress‐stimulated rats by altering gut microbiota. CNS Neuroscience & Therapeutics, 28(9), 1409-1424.

+ Open protocol

+ Expand

Controlled Environment for Male SD Rats

Check if the same lab product or an alternative is used in the 5 most similar protocols

Adult male SD rats (230–250 g) were purchased from Beijing Vital River Laboratory Animal Technology Co., Ltd., and housed in a controlled environment (22 ± 2°C, relative humidity of 60–70%; 12 h/12 h light/dark cycle). All rats received standard laboratory food and water ad libitum. All efforts were made to minimize animal suffering and the number of animals employed. The animal study was reviewed and approved by the Ethics Committees of Peking Union Medical College Hospital and the Chinese Academy of Medical Sciences for the Care and Use of Laboratory Animals (permit no. XHDW-2016-021).

Zhang Y.M., Xu H., Chen S.H, & Sun H. (2021). Electroacupuncture Regulates Endoplasmic Reticulum Stress and Ameliorates Neuronal Injury in Rats with Acute Ischemic Stroke. Evidence-based Complementary and Alternative Medicine : eCAM, 2021, 9912325.

+ Open protocol

+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Revolutionizing how scientists
search and build protocols!