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Lyphocheck whole blood metals control

Manufactured by Bio-Rad
Sourced in United States

Lyphocheck Whole Blood Metals Control is a quality control material used for monitoring the performance of analytical methods for the measurement of metals in whole blood samples. It provides a ready-to-use matrix for verifying the accuracy and precision of laboratory testing procedures.

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2 protocols using lyphocheck whole blood metals control

1

Heavy Metal Analysis Protocol

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Pb, Hg, and Cd analyses were performed as previously described [9 (link)]. In brief, these tests were performed by the Neodin Medical Institute, which had been approved by the Korean Ministry of Labor for Heavy Metal Analysis. Furthermore, the tests used met the requirements of the Korea Occupational Safety and Health Administration, the German External Quality Assessment Scheme, and the U.S. CDC. Pb and Cd levels were measured by graphite furnace atomic absorption spectrometry (model AAnalyst 600; Perkin Elmer, Turku, Finland) using Zeeman background correction, and total Hg levels were determined using a direct mercury analyzer (model DMA-80 Analyzer; Bergamo, Italy) and the gold amalgam method (KCDC 2013). Limits of detection (LODs) were 0.223 μg/dL, 0.05 μg/L, and 0.087 μg/L for Pb, Hg, and Cd, respectively. Commercial standard reference materials purchased from Bio-Rad were used for internal quality assurance and control (Lyphocheck Whole Blood Metals Control; Bio-Rad, Hercules, CA, USA).
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2

Heavy Metal Analysis in Blood Samples

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Blood sampling and Pb, Hg, and Cd analyses were performed by the Neodin Medical Institute, which is certified by the Korean Ministry of Labor for the analysis of heavy metals, and meets the requirements of the German External Quality Assessment Scheme, the U.S. CDC program, and the Korea Occupational Safety and Health Administration (Korea OSHA) program (KCDC, Korea Centers for Disease Control and Prevention 2013). Pb and Cd were measured by graphite furnace atomic absorption spectrometry (model AAnalyst 600; Perkin Elmer, Turku, Finland) using the Zeeman background correction, and total Hg was measured using a direct mercury analyzer (model DMA-80 Analyzer; Bergamo, Italy) and the gold amalgam method (KCDC 2013). Limits of detection (LODs) were 0.223 µg/dL, 0.05 µg/L, 0.087 µg/L for Pb, Hg, and Cd, respectively. No adult sample had a value of below a LOD, and only 4 adolescent samples had Cd values (0.043, 0.064, 0.067, 0.078) below its LOD. For internal quality assurance and control, commercial standard reference materials were purchased from Bio-Rad (Lyphocheck Whole Blood Metals Control; Bio-Rad, Hercules, CA, USA).
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