In this study, 14 HCC (7 males, 7 females; median age, 62 years; range, 22−91 years) who received PT were enrolled. None of them had a history of surgery or irradiation nor clinical evidence of cirrhosis. This study was approved by the Institutional Review Board of our institution.
Patients were placed in the supine position and immobilized with a vacuum cushion with their arms over their heads. Respiratory pattern was neither mentioned nor coached so that the patients breathed freely with no alteration. 4DCT was performed to measure the amount of respiratory motion at the time of treatment planning CT imaging; no artifacts that could interfere with measurement were present. A laser displacement sensor, AZ‐733 V (Anzai Medical, Tokyo, Japan), was used to detect the displacement of a certain point near the patient's navel to obtain the respiratory waveform. The scan range included the entire liver during all respiratory phases. After scanning, a 10‐phase‐gated 4DCT image from 0% to 90% distributed over the whole respiratory cycle was constructed from the row 4DCT data. All CT images were imported into a treatment planning system, XiO‐M R 4.34.02 (Hitachi, Kashiwa, Japan), and registration software,
Focal (Elekta, Stockholm, Sweden).
Aquilion LB (Canon Medical Systems, Otawara, Japan) was used for the CT scans; images were taken in 2‐mm slices.
Kato T., Takemasa K., Ikeda T., Sakagami H., Kato R., Narita Y., Oyama S., Komori S., Yamaguchi H, & Murakami M. (2024). Analysis of respiratory‐induced motion trajectories of individual liver segments in patients with hepatocellular carcinoma. Journal of Applied Clinical Medical Physics, 25(4), e14257.
