Wild type c57bl 6j wt male mice

Wild type C57BL/6J (WT) male mice were purchased from the Janvier Laboratory.
Caspase1/11^-/- (42 (link)) were provided by Seshadri Tara at BASF Bioresearch corporation, Nlrp3^-/- (10 (link)) by Dr. Jürg Tschopp and Gsdmd^-/- (27 (link)) by Dr Petr Broz. Mice were backcrossed 10 times or made on C57BL/6J background. All mice were housed at the animal facility at transgenose institute (TAAM) in CNRS of Orleans, France. For experiments, adults (8-11 weeks old) were kept in sterile, isolated and ventilated cages. All animal experiments followed the French government’s ethical and animal experiment regulations (APAFIS 2020 #26177).

Wild-type C57BL/6J (WT) male mice were purchased from the Janvier laboratory (Janvier Laboratory, France). IFNAR^−/− were provided by Michel Aguet from the Institute of Molecular Biology I, University of Zurich, Switzerland^{49 (link)}, STING^−/− by Glen Barber^{50 (link)}, cGAS^−/− mice by Zhijian Chen^{51 (link)} and TLR9^−/− by Shizuo Akira^{52 (link)}. All mice were backcrossed 10 times or made on C57BL/6 J background and housed in the UPS44-TAAM (CNRS, Orleans, France) animal facility. For experiments, adults (8–12 weeks old) were kept in sterile, isolated and ventilated cages. All animal experiments followed the French government’s ethical and animal experiment regulations and were approved by the “Ethics Committee for Animal Experimentation of CNRS Campus Orleans” (CCO) under number CLE CCO 2015-1088.