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Pirl 1 8 cyclohexil 5 6 dihidro 4h pyrazino 3 2 1 jk carbazole

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Pirl-1 (8-cyclohexil-5,6-dihidro-4H-pyrazino[3,2,1-jk]carbazole) is a heterocyclic organic compound. It consists of a pyrazine ring fused to a carbazole ring system, with a cyclohexyl substituent.

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Lab products found in correlation

Chlorpromazine, by Merck Group (2 mentions) Carbachol, by Merck Group (2 mentions) Alexa fluor 488 conjugated wheat germ agglutinin, by Thermo Fisher Scientific (2 mentions) Bapta am, by Merck Group (2 mentions) Methyl β cyclodextrin, by Merck Group (2 mentions)

2 protocols using pirl 1 8 cyclohexil 5 6 dihidro 4h pyrazino 3 2 1 jk carbazole

1

Investigating Cdc42 Activation Inhibition

Check if the same lab product or an alternative is used in the 5 most similar protocols
Carbachol (CCH), chlorpromazine (CPZ), methyl-β-cyclodextrin (MβCD), and BAPTA-AM were from Sigma. Pirl-1 (8-cyclohexil-5,6-dihidro-4H-pyrazino[3,2,1-jk]carbazole), which inhibits guanine nucleotide exchange on Cdc42, was from Chembridge (San Diego, CA) [26 (link)]. AlexaFluor 488 conjugated wheat germ agglutinin (WGA) was from Invitrogen.
Zachos N.C., Alamelumangpuram B., Lee L.J., Wang P, & Kovbasnjuk O. (2014). Carbachol-Mediated Endocytosis of NHE3 Involves a Clathrin-Independent Mechanism Requiring Lipid Rafts and Cdc42. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 33(3), 869-881.
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2

Investigating Cdc42 Activation Inhibition

Check if the same lab product or an alternative is used in the 5 most similar protocols
Carbachol (CCH), chlorpromazine (CPZ), methyl-β-cyclodextrin (MβCD), and BAPTA-AM were from Sigma. Pirl-1 (8-cyclohexil-5,6-dihidro-4H-pyrazino[3,2,1-jk]carbazole), which inhibits guanine nucleotide exchange on Cdc42, was from Chembridge (San Diego, CA) [26 (link)]. AlexaFluor 488 conjugated wheat germ agglutinin (WGA) was from Invitrogen.
Zachos N.C., Alamelumangpuram B., Lee L.J., Wang P, & Kovbasnjuk O. (2014). Carbachol-Mediated Endocytosis of NHE3 Involves a Clathrin-Independent Mechanism Requiring Lipid Rafts and Cdc42. Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, 33(3), 869-881.
+ Open protocol
+ Expand

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