Log In Sign up
The largest database of trusted experimental protocols

Phenyl isocyanate

Manufactured by Merck Group
Visit Supplier
Sourced in United States

Phenyl isocyanate is a colorless liquid chemical compound that is commonly used in the production of various industrial and laboratory products. It serves as a key intermediate in the synthesis of numerous organic compounds.

Automatically generated - may contain errors

Lab products found in correlation

Dimethyl sulfoxide (dmso), by Merck Group (4 mentions) Aniline, by Merck Group (3 mentions) Diphenyl ether, by Merck Group (2 mentions) Formic acid, by Merck Group (2 mentions) 1 3 diphenylurea, by Merck Group (2 mentions) 1 2 pyridyl piperazine, by Merck Group (2 mentions) Hplc grade acetonitrile, by Merck Group (1 mentions) Zinc oxide, by Merck Group (1 mentions) Aluminium oxide, by Merck Group (1 mentions) Montmorillonite k10, by Merck Group (1 mentions) 3 chloroaniline, by Merck Group (1 mentions) 2 fluoroaniline, by Merck Group (1 mentions) 3 fluoroaniline, by Merck Group (1 mentions) 4 fluoroaniline, by Merck Group (1 mentions) 1 2 dichlorobenzene, by Merck Group (1 mentions) γ valerolactone, by Merck Group (1 mentions) Ft ir 8300 spectrophotometer, by Shimadzu (1 mentions) Absolute ethanol, by Merck Group (1 mentions) Diethyl ether, by Merck Group (1 mentions) Hydrazine hydrate, by Merck Group (1 mentions)

Spelling variants of this product

4,4′-methylenebis(phenyl isocyanate) (4 citations) 4-(dimethylamino)phenyl isocyanate (2 citations) 4,4′-Methylenebis(phenyl isocyanate) (MDI) (2 citations) Phenyl isocyanate (assay grade), (2 citations)

8 protocols using phenyl isocyanate

1

Synthesis of N-phenyl carbamates

Check if the same lab product or an alternative is used in the 5 most similar protocols
Methyl N-phenyl carbamate (CAS: 2603-10-3) was purchased from TCI chemicals. Phenyl isocyanate (≥98%), aniline (≥99%), 1,3-Diphenylurea (98%), 1-(2-Pyridyl) piperazine (≥99%), Dimethyl sulfoxide (anhydrous ≥ 99.9%) and diphenyl ether (≥99%) were purchased from Sigma-Aldrich.
Acetonitrile (HPLC grade), water (HPLC grade), ammonium acetate (≥98%), and formic acid (For LC-MS 98–100%) were all purchased from Sigma-Aldrich for use in analytical equipment (LC).
Catalysts include montmorillonite K10 (H2Al2(SiO3)4−nH2O, surface area 220–270 m2/g), zinc oxide (nanopowder, ≤100 nm, 10–25 m2/g), and aluminium oxide (50–300 mesh, acid, 155 m2/g) purchased from Sigma-Aldrich and Bismuth(III) oxide (nanopowder 99.9%, 3.8–5.5 m2/g) was purchased from Fischer scientific. The catalysts were stored in an oven (110 °C) prior to experiments.
Zamani S., Lange J.P., Kersten S.R, & Ruiz M.P. (2022). Polyurethane Recycling: Conversion of Carbamates—Catalysis, Side-Reactions and Mole Balance. Polymers, 14(22), 4869.
+ Open protocol
+ Expand
2

Synthesis of Functionalized Adamantanes

Check if the same lab product or an alternative is used in the 5 most similar protocols
Triethylamine (BioUltra ≥ 99.5%, CAS 121-44-8), 3-chloroaniline (99%, CAS 108-42-9), cyclohexyl isocyanate (98%, CAS 3173-53-3), phenyl isocyanate (98%, CAS 103-71-9) manufactured by Sigma-Aldrich (St. Louis, MO, USA) were used without purifying.
4-(Trifluoromethoxy) isocyanate (97%, CAS 35037-73-1), aniline (99+%, CAS 62-53-3), 2-fluoroaniline (99%, CAS 348-54-9), 3-fluoroaniline (98%, CAS 372-19-0), 4-fluoroaniline (99%, CAS 371-40-4) produced by the AlfaAesar (Ward Hill, MA, USA) were used without additional purification.
Diethyl ether was purified by well-known methods. trans-4-Amino-(cyclohexyloxy)benzoic acid 7a [2 (link)], 1,3-dehydroadamantane 2a [12 (link)], 1,3-dehydro-5,7-dimethyladamantane 2b [12 (link)], 2-(adamantane-1-yl)-2-phenylacetic acid ethyl ester 3a [15 (link)], 2-(adamantane-1-yl)-2-phenylacetic acid 4a, 1-(isocyanato(phenyl) methyl)adamantane 5a [10 (link)] were obtained by well-known methods.
D’yachenko V., Danilov D., Kuznetsov Y., Moiseev S., Mokhov V., Burmistrov V, & Butov G. (2023). Synthesis and Properties of 1,3-Disubstituted Ureas Containing (Adamantan-1-yl)(phenyl)methyl Fragment Based on One-Pot Direct Adamantane Moiety Inclusion. Molecules, 28(8), 3577.
+ Open protocol
+ Expand
3

Organic Synthesis Reagent Procurement

Check if the same lab product or an alternative is used in the 5 most similar protocols
Aniline (≥99%), 1,2-dichlorobenzene (99%), dimethyl sulfoxide (>99%), 1,3-diphenyl urea (98%), diphenyl ether (99%), γ -valerolactone (98%), phenyl isocyanate (>98%), and 1-(2-pyridyl)piperazine (>99%) were purchased from Sigma-Aldrich. For the analytical equipment, acetonitrile (HPLC grade), ammonium acetate (>98%), formic acid (for LC-MS 98–100%), and water (HPLC grade) were purchased from Sigma-Aldrich.
Zamani S., van der Voort S.H., Lange J.P., Kersten S.R, & Ruiz M.P. (2023). Polyurethane Recycling: Thermal Decomposition of 1,3-Diphenyl Urea to Isocyanates. Polymers, 15(11), 2522.
+ Open protocol
+ Expand
4

Synthesis and Characterization of Organic Compounds

Check if the same lab product or an alternative is used in the 5 most similar protocols
The composition of the C-steel used throughout all experiments was (wt%) 0.20 C, 0.045 P, 0.30 Si, 0.53 Mn, 0.055 S, Fe balance. The corrosive solution (1.0 M HCl) was prepared by direct dilution with double-distilled water.
Malonic diethyl ester, salicylaldehyde, phenyl isocyanate, and hydrazine hydrate (80%) were purchased commercially from Sigma Aldrich, St. Louis MO, USA, and used without any further purification. Absolute ethanol, DMSO, diethyl ether, and all used solvents were purchased from Merck, Mumbai, India. The melting points were reported on a heated stage Gallen Kamp melting point equipment (Gemini Lab, Apeldoom, Netherlands). Elemental C, H, N, and S analyses were carried out on a Fison EA 1108 analyser (Shimadzu, Kyoto, Japan). The infrared (FTIR) spectra were recorded by employing a FTIR.8300 Shimadzu Spectrophotometer (Shimadzu, Kyoto, Japan) by using KBr disc in the frequency range of 4000–400 cm−1. The 1H NMR spectra were recorded on an Ultra-Shield™ 500 MHz NMR Spectrometer (Shimadzu, Kyoto, Japan) using deuterated DMSO-d6s the solvent and tetramethylsilane (TMS) as the internal standard.
Alarfaji S.S., Ali I.H., Bani-Fwaz M.Z, & Bedair M.A. (2021). Synthesis and Assessment of Two Malonyl Dihydrazide Derivatives as Corrosion Inhibitors for Carbon Steel in Acidic Media: Experimental and Theoretical Studies. Molecules, 26(11), 3183.
+ Open protocol
+ Expand
5

Synthetic Routes for Nitrogen-Containing Heterocycles

Check if the same lab product or an alternative is used in the 5 most similar protocols
Thiophene-2-carbonitrile
(Alfa Aeser, 98%), thiophene-2-carbaldehyde (Merck, 93%), N-chlorosuccinimide (Alfa Aeser, 98%), p-anisidine (Alfa Aeser, 99%), aluminum chloride anhydrous (Fluka,
98%), p-toluidine (Adwic, Egypt), hydroxylamine hydrochloride
(Oxford, 98%), aniline (Adwic, Egypt), O-phenylenediamine
(Sigma-Aldrich, 98%), α-naphthylamine (Adwic, Egypt), tetralin
(Alfa Aser, 97%), 2-amino-5-chlorophenol (Sigma-Aldrich, 97%), acetonitrile
(Sigma-Aldrich, HPLC grade), 2-amino-5-methylphenol (Sigma-Aldrich,
98%), phenyl isocyanate (Sigma-Aldrich, 98%), 4-methoxyphenyl isocyanate
(Sigma-Aldrich, 98%), 4-methylphenyl isocyanate (Sigma-Aldrich, 98%),
and 1,1,2,2-tetrachloroethane (Fluka, 95%) were used. Other reagents
and solvents were purchased and used as received unless otherwise
listed.
Mekhemer I.M., Gaber A.A, & Aly M.M. (2020). Production of Amidinyl Radicals via UV–Vis-Light Promoted Reduction of N-Arylthiophene-2-carboxamidoximes and Application to the Preparation of Some New N-Arylthiophene-2-carboxamidines. ACS Omega, 5(44), 28712-28721.
+ Open protocol
+ Expand
6

Fatty Acid Methyl Ester Characterization

Check if the same lab product or an alternative is used in the 5 most similar protocols
Fatty Acid Methyl Ester of Very High Oleic Sunflower Oil (FAMEVHOSO) with 3.32 mmol double bond/g was kindly supplied by the ITERG group (Canéjan, France). The FAMEVHOSO is composed of 83% of oleic acid. Table S1 presents the distribution of fatty methyl esters of unsaturated FAMEVHOSO. Glacial acetic acid (AA), toluene (99%), H2O2 30%, ethyl acetate (99%), and ethanol (99.9%) were obtained from Fisher Scientific (Illkirch-Graffenstaden, France). Amberlyst® 15H (strongly acidic cation exchanger dry), Amberlite® IR120H (strongly acidic hydrogen form), CDCl3, phenylisocyanate (98%), dibutylamine (DBA) (99.5%), HBr (48% in water), HCl (37% in water), and diethylamine (99%) (DEA) were provided by Sigma-Aldrich (Saint-Quentin-Fallavier, France). ethanol absolute (EtOH) was purchased from VWR (Briare, France). All of the chemicals were used without any purification.
Peyrton J., Chambaretaud C, & Avérous L. (2019). New Insight on the Study of the Kinetic of Biobased Polyurethanes Synthesis Based on Oleo-Chemistry. Molecules, 24(23), 4332.
+ Open protocol
+ Expand
7

Polyurethane Synthesis Protocol

Check if the same lab product or an alternative is used in the 5 most similar protocols
Phenyl isocyanate (98%) (PI), p-tolyl isocyanate (PTI), dimethyl sulfoxide (DMSO, anhydrous, 99.9%), D-sorbitol (98%), and glycerol (99%), tin(II) 2-ethylhexanoate (TEH) and toluene were purchased from Sigma-Aldrich (Darmstadt, Germany) and all were used as received except the toluene, which was purified and dried according to the well-known procedure [23 (link)]. The D(+)-sucrose (puriss, Ph. Eur. 6.) was obtained from Reanal (Budapest, Hungary) and dried in a vacuum oven at 40 °C for overnight before use. Methanol (HPLC grade) from Merck (Darmstadt, Germany) was used without any purification.
Nagy L., Vadkerti B., Lakatos C., Fehér P.P., Zsuga M, & Kéki S. (2021). Kinetically Equivalent Functionality and Reactivity of Commonly Used Biocompatible Polyurethane Crosslinking Agents. International Journal of Molecular Sciences, 22(8), 4059.
+ Open protocol
+ Expand
8

Cellulose Characterization via Derivatization

Check if the same lab product or an alternative is used in the 5 most similar protocols
Pyridine (≥ 99.9%, Sigma, USA), phenyl-isocyanate (≥ 99.9%, Sigma, USA), methanol (Stanlab, Poland) and tetrahydrofuran (Chempur, Poland) were used for cellulose derivatisation and SEC analyses. Four different cellulose samples were purchased from Sigma, USA: Sigmacell type 20 (labelled "S20", from cotton linters, product n° 310697), Sigmacell type 50 (labelled "S50", from cotton linters, product n° S5504), Microcrystalline cellulose (labelled "SMC", from cotton linters, product n° 435263), and acid-washed cellulose (labelled "SAW", from fir, product n° 22182). All cellulose samples were milled for 30, 60 and 120 min using a Pulverisette 23 ball-mill (Fritsch, Germany).
Mattonai M., Pawcenis D., Del Seppia S., Łojewska J, & Ribechini E. (2018). Effect of ball-milling on crystallinity index, degree of polymerization and thermal stability of cellulose. Bioresource technology, 270.
+ Open protocol
+ Expand

About PubCompare

Our mission is to provide scientists with the largest repository of trustworthy protocols and intelligent analytical tools, thereby offering them extensive information to design robust protocols aimed at minimizing the risk of failures.

We believe that the most crucial aspect is to grant scientists access to a wide range of reliable sources and new useful tools that surpass human capabilities.

However, we trust in allowing scientists to determine how to construct their own protocols based on this information, as they are the experts in their field.

Ready to get started?

Sign up for free.
Registration takes 20 seconds.
Available from any computer
No download required

Sign up now

Revolutionizing how scientists
search and build protocols!