Standard aluminum sample pans

The thermal analysis of trans-resveratrol nanocrystals, both the lipid-coated and uncoated counterparts, was carried out using a DSC/7 differential scanning calorimeter (Perkin-Elmer, Branford, CT, USA) that was equipped with a TAC 7/DX instrument controller and the Pyris Manager program. The instrument was calibrated with indium for melting point and heat of fusion before analyses took place. A heating rate of 10 °C per minute was used in the 25–280 °C temperature range. The thermal behavior was studied by heating roughly 3 mg of the samples in standard aluminum sample pans (Perkin-Elmer), with an empty aluminum pan being used as the reference standard. Analyses were carried out under nitrogen purge and triple runs were performed for each sample.

Differential scanning calorimetry (DSC) was carried out by means of a Perkin Elmer DSC/7 differential scanning calorimeter (Perkin-Elmer, Waltham, MA, USA) equipped with a TAC 7/DX instrument controller. The instrument was calibrated with indium for melting point and heat of fusion. A heating rate of 10 °C/min was employed in the 25–250 °C temperature range. Standard aluminum sample pans (Perkin-Elmer) were used; an empty pan was used as a reference standard. Analyses were performed in triplicate on 3 mg freeze-dried samples under a nitrogen purge.

Differential Scanning Calorimetry (DSC) was carried out by means of a Perkin Elmer DSC/7 differential scanning calorimeter (Perkin-Elmer, Waltham, MA, USA) equipped with a TAC 7/DX instrument controller (Perkin-Elmer). The instrument was calibrated with indium for melting point and heat of fusion. A heating rate of 10 °C/min was employed in the 25–300 °C temperature range. The standard aluminum sample pans (Perkin-Elmer) were used. An empty pan was used as a reference standard. Analyses were performed in triplicate using about 3 mg freeze-dried samples under nitrogen purge.