Categorical variables were reported as number (n) and proportion (%) and compared using Pearson’s χ
2 analysis. Continuous variables were reported as median and range. The RFS and OS were calculated using the Kaplan–Meier method and compared using the log-rank test. The Cox proportional hazards model was used to identify independent risk factors associated with RFS and OS by multivariate analysis. A
P value < 0.05 was set as the significance threshold.
To balance the background risks between the two study groups, we performed 1:1 propensity score matching (PSM) using a caliper of 0.1 and to include age, gender, etiology, alanine aminotransferase, portal hypertension, Child–Pugh grade, AFP, extent of hepatectomy, intraoperative blood transfusion, histological severity of cirrhosis, microvascular invasion, and tumor differentiation. The PSM model was generated using the PSM program through the
SPSS R-Plugin. The analysis applied single nearest-neighbor matching.
For all tests, a 2-tailed
P < 0.05 was considered statistically significant. Statistical analysis was performed using the
SPSS 26 statistical software (SPSS, Inc., Chicago, IL, USA).
Liang B.Y., Gu J., Xiong M., Zhang E.L., Zhang Z.Y., Chen X.P, & Huang Z.Y. (2021). Tumor size may influence the prognosis of solitary hepatocellular carcinoma patients with cirrhosis and without macrovascular invasion after hepatectomy. Scientific Reports, 11, 16343.